Exam (elaborations)
ONS Chemotherapy Course questions and answers
- Course
- Institution
ONS Chemotherapy Course questions and answers
[Show more]
Seller
Follow
EXAMQA
Reviews received
Content preview
ONS Chemotherapy Course5-fluorouracil - correct answer-Antimetabolite
**leucovorin given concurrently
**take year round photosensitivity precautions
**cardiotoxicity
**Bolus can cause increased mucositis so have patient suck on ice chips for 10-15 min pre
and post. Can also cause hyperpigmentation at peripheral site
**Continuous can cause N/V/D and photosensitivity
adjuvant therapy - correct answer-used after the primary treatments have been completed to
decrease the chance that a cancer will recur
Agranulocytes - correct answer-T lymphocytes, B Lymphocytes, and Monocytes
Alkylating Agents - correct answer-synthetic chemicals containing alkyl groups that attack
DNA, causing strand breaks
Side Effects:
-secondary malignancies
-hypersensitivity reactions
-GI toxicities (N/V/D)
-highly emetogenic
-Renal Toxicity (need BUN and Creatinine prior)
Anthrayclines - correct answer-interfere with enzymes necessary for DNA to replicate
**work in all phases of the cell cycle
**Lifetime dose limits to prevent permanent cardiotoxicity and pulmonary fibrosis
**Daunorubicin, Doxorubicin, Epirubicin, Idarubicin
Antimetabolites - correct answer-function by blocking DNA and RNA growth
*work in the S phase therefore very effective in fast growing tumors
**Vidaza, Xeloda, 5 FU, Cytarabine, Dacogen, Methotrexate
**can cause photosensitivity, GI toxicities, and Hand Foot and Mouth
, **vigorous hydration especially with high tumor burden to prevent TLS
Azacitidine (Vidaza) - correct answer-Antimetabolite
**IV or SC
**IV can cause hypokalemia, weakness, rigors and petechiae.
Bleomycin - correct answer-Nonanthracycline;antitumor antibiotics
**lifetime dose of 400 units for pulmonary fibrosis
**those with lymphoma have a greater risk of anaphylaxis (2 test doses are often done)
**watch for SOB, hyperpigmentation of skin, nail changes, erythema
**protect skin from exposure
**risk for pulmonary toxicity if given oxygen during procedures
Capecitabine (Xeloda) - correct answer-Antimetabolite
**oral 5 FU
**take within 30 minutes of meal with water
**associated with Hand Foot Mouth
**can increase INR with Coumadin
**can increase bilirubin
Carboplatin (Paraplatin) - correct answer-alkylating agent-platinum based
**Hypersensitivity reaction
**harder for those >65
**harder on kidney function
**cause neurotoxicity
**Can cause hearing loss
**first 24 hours nausea
Cell Mediated Immunity - correct answer-Type of immunity produced by T cells that attack
infected or abnormal body cells.
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller EXAMQA. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $7.99. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
75323 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now