Exam (elaborations)
M02-FL03 Vasodilators
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M02-FL03 Vasodilators
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M02-FL03 VasodilatorsA cardiac reflex in response to hypotension - ANS-Tachycardia, stimulation of RAA
A drug used to prolong the action of lidocaine - ANS-epinephrine
A high dose of nitroglycerin does this - ANS-Decreases pre-load and afterload
A loading dose acheives steady-state: True or False - ANS-FALSE
ACE inhibitor effects in the kidneys will not result in renal decompensation as long as
this occurs - ANS-Cardiac output increases (in the healthy heart) as a result of
decreased afterload
ACE inibitors are associated with reno protection in pateints with progressive renal
disease (T or F) - ANS-TRUE
Afterload vessels - ANS-precapillary arterioles
Amlodipine acts as a negative inotrope (T or F) - ANS-FALSE
Amlodipine may inhibit drug metabolizing enzymes (T or F) - ANS-FALSE
An approach to limit the effect of nitroglycerin to preload reduction - ANS-Low dose
An indicator of acute renal decompensation following ACE inhibitor therapy -
ANS-Increased serum creatinine
Capacitance vessels - ANS-venules
Capacitance: venous or arterial? - ANS-Venous
Common adversity of afterload reducer - ANS-Hypotension
Drugs which increase the risk of renal decompensation following ACE inhibitor therapy -
ANS-NSAIDs, aminoglycosides, diuretics
, Enalapril is not absorbed in this species - ANS-Horse
Half-life of amlodipine in dogs - ANS-30 hrs
Hypertension is a common malady of dogs (T or F) - ANS-FALSE
If designing a loading dose, and the target concentration is known, the dose is
calculated based on: - ANS-Volume of distribution and oral bioavailability
Impact of inhibiting cAMP in smooth muscle - ANS-contraction
Impact of stimulating cAMP in smooth muscle - ANS-relaxation
Mechanism by which acepromazine causes vasodilation - ANS-dc
Mediators causing vasoconstriction of arterioles - ANS-Angiotensin II, vasopressin,
endothelin, epi and norepi
Nitrates are convertid to nitric oxide in the vascular endothelial cell (T or F) - ANS-TRUE
Nitroglycerin is orally bioavailable (T or F) - ANS-FALSE
Nitroprusside is used for emergency treatment of this - ANS-Increased afterload,
inlcuding hypertension
Other than half-live, a reason for delayed response to amlodipine - ANS-Binding and
saturating receptors
Preload vessels - ANS-Venules
Resistance vessels - ANS-precapillary arterioles
Resistance: venous or arterial? - ANS-Arterial
Risk factors for renal decompensation following ACE inhibitor therapy - ANS-Renal
disease, severe myocardial disease, hyponatremia
Standard routes of nitroglycerin therapy in animals - ANS-Transdermal
The active form of enalapril - ANS-Enaliprat
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