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Exam (elaborations)

FoEM CBR22- Infectious Disease Exam

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FoEM CBR22- Infectious Disease Exam Dx and Tx: Fish tank granuloma Mycobacterium marinum, Tx: Clarithromycin + Ethambutol OR Rifampin Dx: Rose thorn injury and rash Sporothrix schenckii. Tx: Itraconazole (amphotericin B if systemic) Dx and Tx: Dog and cat bite with rapid infection Pas...

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  • June 22, 2024
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  • 2023/2024
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FoEM CBR22- Infectious Disease Exam
Dx and Tx: Fish tank granuloma
Mycobacterium marinum, Tx: Clarithromycin + Ethambutol OR Rifampin


Dx: Rose thorn injury and rash
Sporothrix schenckii. Tx: Itraconazole (amphotericin B if systemic)


Dx and Tx: Dog and cat bite with rapid infection
Pasteurella multocida. Tx: Amoxicillin-Clavulanate (augmentin —> "dog-mentin")


Dx: Reptile bites and infection
Salmonella


Dx: Sickle cell disease and joint pain
Salmonella osteomyelitis


Dx: Cat scratch fever
Bartonella henselae. Tx: doxy; azithromycin in pregnancy


Dx and Tx: Human bite and infection
Eikenella corrodens. Tx: amoxicillin-clavulanate


Dx: Gastroenteritis on a cruise ship
Norwalk virus


Dx: Gastroenteritis at a daycare
Rotavirus, (remember, there is a vaccine now).


Compare general Dx and Tx of toxin-mediated vs. invasive bacterial diarrheal illness
Toxin: abrupt onset, watery, non-bloody; Tx IVF, ± loperamide, ± Cipro (prolonged/severe ssx).
Invasive: gradual onset, bloody, systemic sx; Rx: IVF, ± Cipro UNLESS kids or elderly patients with
possible E. coli O157:H7 (can increase risk of HUS)


Dx: Watery diarrhea + eggs/mayo
Staph. aureus (toxin)


Dx: Watery diarrhea + fried rice
Bacillus cereus (toxin)


Dx and Tx: Diarrhea + flatulence + recent hiking and drinking from a freshwater stream
Giardia lamblia. Parasitic infection. Test for it w/ a stool antigen (not ova and parasite). Tx:
Metronidazole / tinidazole. People who are risk: hikers, children at daycare, and oral-anal sexual
conduct.

, Dx: Watery diarrhea + travel
Enterotoxigenic E. coli (toxin, ETEC); if no blood in diarrhea, give 1 dose of Cipro 750 mg. If pt traveled
to southeast Asia this is likely campylobacter and give 1,000 mg of azithromycin


Dx: Watery diarrhea + meat/poultry
Clostridium perfringens (toxin)


SSx, Dx, Tx: Watery diarrhea + dark meat fish + rash/itching
Scombroid (histamine fish toxicity). Dark fleshed, peppery tasting fish: tuna, mahi-mahi, mackerel.
Excess histidine on fish broken down by bacteria to histamine. SSx: Histamine ingestion leads to
anxiety, flushing, headache, palpitations, vomiting. Tx: antihistamines


Dx: Watery diarrhea + carnivorous fish + neuro ssx
Ciguatera (toxin causes neuro ssx) - "hot cold reversal"


Dx: Bloody diarrhea + undercooked eggs/chicken + relative bradycardia
Salmonella typhi (invasive), cafeteria outbreaks, classically with high fever and relative bradycardia;
can cause osteomyelitis in sickle cell patients.


Dx: Bloody diarrhea (severe) + high fever + institutionalized
Shigella (invasive); can cause seizures in kids


Dx and Tx: Bloody diarrhea + followed by weakness
Campylobacter (invasive). Associated: appendicitis mimic & Guillain-Barré; Tx: Azithro/Erythro
(resistance to cipro)


Dx: Bloody diarrhea + farm animals + appendicitis ssx
Yersinia (invasive); pseudoappendicitis (appy mimic) can cause terminal ileitis


Dx: Bloody diarrhea + undercooked seafood + alcoholic who gets very sick
Vibrio parahaemolyticus (invasive)


Dx: Bloody diarrhea + poorly cooked ground beef/raw milk
E. coli O157:H7, associated with TTP (adults) and HUS (kids); NO ANTIBIOTICS


Dx: Rice-water stools + contaminated water
Vibrio cholerae (toxin). Oral rehydration tablets.


Dx and Tx: Profuse diarrhea after recent antibiotics
Clostridium difficile (invasive). Tx: PO vanco is first line now


Dx: Diarrhea + AKI ± low platelets
E. coli O157:H7 causing TTP/HUS

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