100% satisfaction guarantee Immediately available after payment Both online and in PDF No strings attached
logo-home
Previously searched by you
Previously searched by you
logo
Acid Base Questions with 100% Actual correct answers | verified | latest update | Graded A+ | Already Passed | Complete Solution $7.99   Add to cart
Quickly navigate to
Preview
  2.  
  3. All Summer Modules Studies 2024
  4.  
  5. All Summer Modules Studies 2024
  6.  
  7. All summer modules studies 2024

Exam (elaborations)

Acid Base Questions with 100% Actual correct answers | verified | latest update | Graded A+ | Already Passed | Complete Solution

1 review
 7 views  0 purchase
  • Course
  • All summer modules studies 2024
  • Institution
  • All Summer Modules Studies 2024

Acid Base Questions with 100% Actual correct answers | verified | latest update | Graded A+ | Already Passed | Complete Solution

Preview 2 out of 8  pages

Document information

  • June 19, 2024
  • 8
  • 2023/2024
  • Exam (elaborations)
  • Questions & answers

Subjects

  • acid base questions with 100 actual correct answe

Written for

  • All summer modules studies 2024
  • all summer modules studies 2024
  • All summer modules studies 2024
All documents for this subject (274)

1  review

review-writer-avatar

By: EXAMQA • 4 months ago

Seller

avatar-seller
Hkane

Reviews received

Content preview

Acid Base
Acidosis from HCO and CO2
Drop in HCO3- or increase in pCO2 cause acidosis
H+ rise is limited by
HCO3-, proteins, phosphate, carbonate
pH buffering
Bicarb
HPO4 2-
Proteins
Respiratory
Renal
Kidneys in acid base
Regulate bicarb concentration
Can reabsorb all filtered HCO3-
Produce new bicarb
Excrete acids
H+ excretion
99.9% H+ that is excreted is bound to acid
most as NH4+ and HPO4-
Minimum pH is 4.5
Titratable acids
Measure the amount of NaOH needed to bring the urine pH back to pH of blood
Amount of H+ that are excreted combined with urinary buffers
usually H2PO4-
Bowman's Capsule pH
7.4
Mostly H2PO4-
Ammonia
NH4+ is the preferred from because pKa is 9, so it will almost always be in NH4+
PCT pH
H+ secretion by NHE3 (2/3) and H+ ATPase (1/3)
pH is around 6.7
NH3 diffuses and binds secreted H+
TDL pH
pH increases to 7.4 since water is reabsorbed but nothing else
NH4+ can leak out
TAL pH
back to 6.7
H+ secreted by NHE3, NBC1n
Reabsorbs NH4+, paracellulary
NHE4 at basolateral allows recycling of NH4+
Distal nephron pH
HCO3- reabsorbed, titratable acid is formed

, Ammonia diffuses and NH3 by Rhcg and Rhbg rushed out to capture H+ that is
secreted
Intercalated cells pH
Type A secretes acid
Facilitates H+ secretion by IC-A
Increase in systemic acidity leads to increase H+ secretion
If alkalosis -> secrete more bicarb
Regulation of HCO3- PCT
Acidemia -> inc NHE3 and basolateral transport HCO3- and ammoniagenesis
Ag II -> Inc NHE3 and NBC
Hypokalemia -> inc H+ secretion -> inc HCO3- reabsorption
Parathyroid -> inhibit NHE3
Catecholamines-> inc NHE3 -> H+ secretuin and HCO3- reabsorption
Regulation of HCO3- TAL
10% filtered out
increased by acidosis
Volume contraction and metabolic alkalosis
When volume is down solution gets concentrated more Bicarb increases pH
Aldosterone -> secrete K and phosphate, more alkalosis
Cl- rneal handling of HCO3-
Hypochloremia accompanied with hypokalemia -> more HCO3- reabsorb and H+
secretion
Hypochloremia alone limits Pendrin secretion of HCO3- and limits NCC -> distal
nephron secretion of H+ (ENaC used more and create more of a negative charge
that pulls out H+)
Thiazide
Increase absorption of Na+ by ENaC
DCC is inhibited
Leads to Cl- depletion from vomiting, incomplete secretion of bicarb
Volume decrease -> increase HCO3- reabsorption -> alkalosis
Decrease in pH
Increases
NHE3
NBC
AE1
H+ ATPase
Ammonia synthesis

Glutamine transporters, glutamate dehydrogenase, PEPCK, NKCC2, Rhcg

The benefits of buying summaries with Stuvia:

Guaranteed quality through customer reviews

Guaranteed quality through customer reviews

Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.

Quick and easy check-out

Quick and easy check-out

You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.

Focus on what matters

Focus on what matters

Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!

Frequently asked questions

What do I get when I buy this document?

You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.

Satisfaction guarantee: how does it work?

Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.

Who am I buying these notes from?

Stuvia is a marketplace, so you are not buying this document from us, but from seller Hkane. Stuvia facilitates payment to the seller.

Will I be stuck with a subscription?

No, you only buy these notes for $7.99. You're not tied to anything after your purchase.

Can Stuvia be trusted?

4.6 stars on Google & Trustpilot (+1000 reviews)

78075 documents were sold in the last 30 days

Founded in 2010, the go-to place to buy study notes for 14 years now

Start selling
$7.99
  • (1)
  Add to cart