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pharm sem 2 final new info Questions with 100% Actual correct answers | verified | latest update | Graded A+ | Already Passed | Complete Solution

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pharm sem 2 final new info Questions with 100% Actual correct answers | verified | latest update | Graded A+ | Already Passed | Complete Solution

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  • June 19, 2024
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  • 2023/2024
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pharm sem 2 final new info
1st gen antipsychotics MOA - ✅✅
-antagonize dopamine D2 receptors in the
brain, in mesolimbic pathway
reduce dopamine neurotransmission

2nd gen antipsychotics MOA - ✅✅ -similar to 1st gen but also antagonize
serotonin 5-HT2A receptors in greater extent

5HT2 antagonists MOA - ✅✅ -block the activity of serotonin 2 receptors,
modulated neurotransmission, leading to changes in mood and emotional
status

✅✅-30 mg/d
abilify max dose -

abilify MOA - ✅✅-SGA
partial agonist at D2 and the 5-HT1A receptors, and antagonist at 5-HT2
receptors

acamporsate CI and monitoring - ✅✅-CI: CrCl < 30
monitor for depression

acamporsate MOA - ✅✅ -may restore balance btw neuronal excitation and
inhibition via effects on GABA and glutamate

adderall MOA - ✅✅ -sympathomimetic amines cause release of
catecholamines from presynaptic terminals, and inhibit catecholamine
reuptake
primarily dopamine

AE of antipsychotics - ✅✅ -hyperprolactinemia: resulting in menstrual
irregularities, galactorrhea, and sexual dysfunction

AE of venlafaxine -✅✅-HTN at higher doses
alpha 2 agonist AE - ✅✅-caution for rebound HTN (especially with abrupt
withdrawal)

, alpha 2 agonist BBW - ✅✅ -obstetrical, postpartum, or perioperative use d/t
risk of hemodynamic instability

alpha 2 agonist indications -✅✅ -ADHD predominately
hyperactivity/impulsivity 6-17 y/o

alpha 2 agonists MOA (clonidine and intuniv) - ✅✅-alpha antagonist effect in
hypothalamus and medulla
stimulates alpha 2 adrenergic receptor

ambien BBW - ✅✅-complex sleep behavior- d/c immediately if occur
ambien CI - ✅✅-3rd trimester pregnancy, concurrent alc/CNS depressant
use, abrupt withdrawal

✅✅-megesterol, dronnabinol
appetite stimulants -

BBW of lithium - ✅✅-pt ed. on maintaining adequate Na+ and hydration
status
renal, thyroid, and serum lithium should be monitored
narrow therapeutic index, dose adjustment may be necessary based on
response and tolerability

benzodiazapines MOA - ✅✅-binds to benzodiazepine receptors, enhances
GABA effects

benzos BBW - ✅✅ -addiction, abuse and misuse/dependence and
withdrawal rxns
do not prescribe long term

brupropion CI - ✅✅ -seizure disorders
hx of anorexia and bulimia

✅✅-respiratory depression, asthma, GI obstruction
buprenorphine CI -

buprenorphine MOA - ✅✅-opioid agonist-antagonist

bupropion MOA - ✅✅-inhibition of reuptake of dopamine and NE

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