Anterior Inferior Cerebellar Artery (AICA) - answer-Feeds anterior inferior parts of the
cerebellum
Symptoms of AICA Stroke - answer-Lateral Pontine Syndrome: vertigo, vomiting,
nystagmus, falling towards the side of the lesion, ipsilateral loss of sensation to the face,
ipsilateral facial paralysis, ipsilateral hearing loss
Posterior Inferior Cerebellar Artery (PICA) - answer-Feeds cerebellum, superior section
of the medulla,. Choroid plexus and fourth ventricle
Symptoms of PICA Stroke - answer-Wallenburg Syndrome (lateral Medullary
Syndrome): Loss of pain and temperature sensation in the contralateral trunk and
ipsilateral face
Basilar Artery - answer-An artery, formed by the fusion of the vertebral arteries, that
supplies blood to the brainstem (medulla and pons) and to the posterior cerebral
arteries.
Symptoms of Basilar Artery Stoke - answer-Coma, quadriparesis, ataxia, dysarthria, CN
dysfunction and visual deficits, Locked in Syndrome, Intranuclear Opthalmoplegia, gaze
paresis, Millard Gulber Syndrome CN VI VII damage (diplopia facial weakness, loss of
corneal reflex), Nausea, vomiting, diplopia, gaze palsy, dysarthria,. vertigo, tinnitus,
hemiparesis, and quadriplegia.
,Anterior Cerebral Artery (ACA) - answer-Feeds the media portion of the frontal and
parietal lobes as well as the corpus callosum
Symptoms of ACA Stroke - answer-Contralateral motor/sensory deficits impacting legs
> arms
Middle Cerebral Artery (MCA) - answer-Feeds majority of the frontal, parietal, and
temporal lobes, basal ganglia, internal capsule. It is divided M1 - M4
Symptoms of MCA Stroke - answer--Aphasia if dominant hemisphere
-Neglect if non-dominant hemisphere
-Contralateral motor/sensory loss of face/arm/leg with Arms > Legs
-Anosognosia: neglect or lack of self awareness
Venous Vascular Anatomy - answer-Venous channels enter into venous sinuses located
in the Dura matter.
Superior Sagittal Sinus - answer-Travels posteriorly between the cerebral hemispheres
towards the occiput
Straight Sinus - answer-Travels along the tentorium, draining blood from the superior
cerebellar veins.
Transverse Sinus - answer-Travels along the base of the occiput laterally and forwardly
Sigmoid Sinus - answer-Begins beneath the temporal bone and travels to the jugular
foramen where it becomes the internal jugular veins
Stroke Pathophysiology - answer-Arterial blood flow to the brain tissue fails to meet
metabolic demands resulting in cell damage or death. ISCHEMIA FIRST THEN
INFARCT.
Penumbra - answer-Zone surrounding the core infarct, damaged by ischemia but not
yet infarcted
---- functionally silent yet metabolically active
Hypoxia leading to Necrotic Pathway - answer-Cell energy failure
, Hypoxia leading to Apoptotic Pathway - answer-Programmed cell death in the
penumbral zone
ICH Stroke Pathophysiology - answer-Occurs when a cerebral blood vessel opens
abnormally and spills blood into brain tissue.
Classification of ICH Brain Injury - answer-Primary Brain Injury: Direct result of the
hematoma
Secondary Brain Injury: Hours or days after ICH, mass effect causes mechanical
disruption and damage to cell membranes
SAH Stroke Pathophysiology - answer-Aneurysm from s in the cerebral vasculature and
ruptures, resulting in blood spilling in the subarachnoid space
Saccular Aneurysm - answer-narrow neck, widened dome -- Most Common
Fusiform Aneurysm - answer-Outpouching of the vessel without a distinct neck --- Less
common
Early Brain Injury - answer-Hours and first several days after aneurysm rupture cerebral
edema forms, injury results from decreased cerebral blood flow
Cerebral Vasospasm (Delayed Cerebral Injury) - answer-Large Vessel Spasm generally
begins on day 4 continues up to 21 days
Brain Requirements - answer-20% of the body's Oxygen
15% of the body's Cardiac Output
Moderate Ischemia (the penumbra): 20 - 30 mL/100 g/min
Severe ischemia and Cell Death: 0 - 10 mL/100 g/min
Large Vessel occlusion - answer-Embolic: develop elsewhere and travel to blood vessel
in the brain
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