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GMS 6531 Homework.

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Exam of 9 pages for the course 6521 Advanced Pharmacology Final at 6521 Advanced Pharmacology Final (GMS 6531 Homework.)

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  • June 15, 2024
  • 9
  • 2023/2024
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GMS 6531 Homework
The majority of hormones secreted by the hypothalamus affect what structure? -
ANS-Anterior pituitary

The pineal gland secretes what hormone? - ANS-melatonin

Vitamin D synthesis is completed in what structure? - ANS-Kidneys

Osteocalcin is which type of hormone? - ANS-Peptide

Which drug would be used to help maintain body mass during treatment for HIV? -
ANS-Somatropin

Octreotide mimics a hormone released from which structure? - ANS-Hypothalamus

Which drug blocks the effects of GH excess without altering GH expression? -
ANS-Pegvisomant

Which drug would be used to treat unwanted lactation that is not associated with
pregnancy or childbirth? - ANS-Bromocriptine

On-and-off dosing of GnRH would result in the release of FSH from which structure? -
ANS-Anterior pituitary

Leuprolide stimulates secretion from which structure? - ANS-Anterior pituitary

Ganirelix inhibits secretion from which structure? - ANS-Hypothalamus

The hormone used to artificially induce labor in pregnant women is naturally stored and
release by which structure? - ANS-Posterior pituitary

A lack of which hormone would result in the elimination of abnormally large amounts of
urine? - ANS-Vasopressin

Which compound would be more appropriate for treating hemophilia A in a patient with
high blood pressure? - ANS-Desmopressin

Through which receptors does desmopressin exert the majority of its effects? - ANS-V2

, What structure produces corticosteroids? - ANS-Adrenal gland

Cortisol production (or administration) produces a feedback loop that effects its own
production. Is this a positive- or negative-feedback loop? - ANS-Negative

Where are glucocorticoid receptors located? - ANS-Intracellularly

Do corticosteroids generally increase or decrease immune and inflammatory response?
- ANS-Decrease

Are larger doses of corticosteroids required for replacement therapy or to achieve an
anti-inflammatory response? - ANS-Anti-inflammatory response

A patient with adrenal insufficiency is being prescribed oral hydrocortisone as a
monotherapy. Which form of insufficiency do they likely have? - ANS-Secondary adrenal
insufficiency

What glucocorticoid is available OTC to treat allergic reactions to mosquito bites? -
ANS-Hydrocortisone

What can cause glucocorticoid related toxicity? - ANS-Both continued use and
withdrawal of glucocorticoids

Which drug would be used to treat mineralocorticoid insufficiency? -
ANS-Fludrocortisone

What drugs would be used to treat elevated levels of mineralocorticoids? -
ANS-Spironolactone

What do the 3 and 4 denote in the thyroid hormones T3and T4? - ANS-Their number of
iodine atoms

A patient suffering from a thyroid disorder that feels constantly exhausted is most likely
suffering from which condition? - ANS-Hashimoto's thyroiditis

Which form of hyperthyroidism is an autoimmune disease? - ANS-Graves' disease

Which form of hyperthyroidism is treated almost exclusively through symptom
management? - ANS-Subacute thyroiditis

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