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BICH 411 Exam 1 (1).

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BICH 411 Exam 1 (1).

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  • June 15, 2024
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  • 2023/2024
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BICH 411 Exam 1
Glycolysis is an anabolic pathway (T/F) - ANS-False

The last reaction of glycolysis is catalyzed by: - ANS-Pyruvate Kinase

Which of the following intermediates of glycolysis are high energy compounds?
A. Glucose 6-phosphate
B. Fructose 1,6-bisphosphate
C. Dihydroxyacetone phosphate
D. 1,3-Bisphosphoglycerate - ANS-1,3-Bisphosphoglycerate

The conversion of glyceraldehyde 3-phosphate into 1,3-bisphosphoglycerate involves: -
ANS-the formation of a covalent thioester intermediate

the conversion of dihydroxyacetone phosphate into glyceraldehye 3-phosphate
involves: - ANS-an enediol intermediate

What are the final products of aerobic catabolism of glucose? - ANS-CO2 and H2O

The 9th reaction of glycolysis is catalyzed by: - ANS-Enolase

(T/F) the first committed step of glycolysis is catalyzed by hexokinase - ANS-False

Which of the following is not a substrate of Hexokinase?
A. Fructose
B. Glucose
C. Mannose
D. Galactose - ANS-Galactose

The first committed step of glycolysis is catalyzed by: - ANS-Phosphoglycerate kinase

The conversion of 3-phosphoglycerate into 2-phosphoglycerate invoves: - ANS-a
phosphorylated histine residue

Enolase catalyzes which reaction - ANS-the dehydration of 2-phosphoglycerate

Which of the following enzymes catalyze an irreversible reaction?
A. Phosphoglucose isomerase

, B. Phosphofructokinase-1
C. Aldolase
D. Glyceraldehyde-3-phosphate dehydrogenase
E. Phosphoglycerate kinase - ANS-Phosphoglucose isomerase

Lactate produced by anaerobic muscle tissue is:
a. stored in muscle until oxygen is available.
b. carried by the blood to the liver for gluconeogenesis and converted to glucose.
c. further reduced to glycerol in muscle.
d. transferred to erythrocytes to release oxygen from hemoglobin.
e. none of the above. - ANS-B. carried by the blood to the liver for gluconeogenesis and
converted to glucose

(T/F) Glycolytic enzymes are found in the mitochondria - ANS-False

(T/F) Glycolysis is an exergonic process - ANS-True

The oxidation of one molecule of glucose by anaerobic glycolysis yields a net of: -
ANS-2 moles of lactate and 2 moles of ATP

The three irreversible steps of glycolysis are catalyzed by: - ANS-hexokinase,
phosphofructokinase-1, pyruvate kinase

Under anaerobic conditions, skeletal muscle generates lactate from pyruvate to: -
ANS-Regenerate NAD+ for further glycolysis

The reaction catalyzed by glyceraldehyde-3-phosphate dehydrogenase involves: -
ANS-the formation of a covalent thioester intermediate

Glucokinase:
A. has a Km for glucose considerably greater than the normal blood glucose
concentration
B. is found in the muscle tissue
C. is inhibited by glucose-6-phosphate
D. is an isozyme of phosphofructokinase
is metabolically important only when glucose concentration is low - ANS-A. has a Km for
glucose considerably greater than the normal blood glucose concentration

Which of the enzymes listed below is used in both gluconeogenic and glycolytic
pathways?

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