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"Unlocking Life's Code: The Human Genome Project Journey"

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"Unveiling Nature's Manuscript: The Human Genome Project - A Journey into the Blueprint of Humanity!"

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  • June 9, 2024
  • 8
  • 2023/2024
  • Class notes
  • Dr devi
  • All classes
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Human Genome Project

 The identity of each individual is determined by the specific genetic
make-up of genetic sequences lies in the DNA.



 If two individuals differ, then their DNA sequences should also be
different, at least in some places of the DNA.



 This assumptions led the scientists to find out the complete sequence
of DNA present in human genome.



 Advances in genetic engineering techniques help the scientists to
isolate and clone DNA pieces and find out the nucleotide sequences of
these fragments.



 The human genome project was launched on October 1, 1990 and
completed in the year 2003.



 The US department of Energy and National Institute of health
embarked and co-ordinated this project.



 The total estimated cost of project was 9 billion US dollars.



 Through this project 3 x 10^9 bp human genome was identified and
sequenced



 For the storage of enormous data generated through this project
requires some 3300 books, each with 1000 pages and each page
contained 1000 letters.

,  The use of high speed computational devices for data storage, retrieval
and analysis of data help the processes faster and easier.



 A new branch of science, the Bioinformatics was developed along with
this HG project.



Goals of HGP.


 To identify all the genes, approximately 20,000-25,000 genes in human
DNA.



 To determine the sequences of the 3 billion chemical base pairs that
used in the make up human DNA.



 To store the gathered information in databases



 To improve the tools for data analysis.



 To transfer related technologies to other sectors, such as industries.



 To solve, the ethical, legal and social issues (ELSI) that may arise from
the project.



 The Human Genome Project (HGP) was completed in 2003.



 During the early years of the project, the Welcome Trust (UK) joined the
project as a major parthe later on Japan, France, Germany, China and
some other countries also joined in the project.

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