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MMG 409 exam 4(All solved)

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  • Course
  • MMG 409
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  • MMG 409

cytoskeleton correct answers network of fibrous elements found in the cytoplasm of eukaryotic cells Microfilaments correct answers polymers of the protein actin that are arranged into bundles and networks microtubules correct answers long hollow tubes formed by polymers of the protein tubulin...

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  • May 4, 2024
  • 5
  • 2023/2024
  • Exam (elaborations)
  • Questions & answers
  • MMG 409
  • MMG 409
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sh3rrymagdah
MMG 409 exam 4(All solved)
cytoskeleton correct answers network of fibrous elements found in the cytoplasm of eukaryotic cells
Microfilaments correct answers polymers of the protein actin that are arranged into bundles and networks
microtubules correct answers long hollow tubes formed by polymers of the protein tubulin
intermediate filaments correct answers tissue specific rope like structures made of related but tissue specific subunit proteins
microvilli correct answers exisit as a tight bundle of filaments making up the core of microvilli
cell cortex correct answers less ordered network beneath the plasma membrane that provides support and organization
adheren belts correct answers form a contractile band around the cell to provide strength to the epithelium
lamellipodium/filopodia correct answers in migrating cells microfilaments are found at the front of the cell in the leading edge from which bundles of filaments may protrude
stress fibers correct answers contractile microfilaments involved in cell migration
phagocytosis correct answers contractile microfilaments to engulf and internalize pathogens
moving endocytic vesicles correct answers short bursts of actin filament assembly can power movement of endocytic vesicles away from the plasma membrane
contractile ring correct answers forms and contracts to generate two daughter cells in cytokinesis
+ end of actin correct answers the ATP binding cleft of the terminal actin contacts the neighboring subunit
the - end of actin correct answers the cleft is exposed to surrounding solution
demonstrates the polarity of actin correct answers decoration experiments
nucleation phase correct answers lag period in which G-actin subunits combine into dimers elongation phase correct answers the short oligomer rapidly increases in length by addition of actin monomers to both ends
steady state phase correct answers G actin monomers exchange with subunits at the filament ends but there is no net change in the total light of filaments
critical concentration correct answers the concentration at which filaments are formed
which end of actin filaments will it grow faster? correct answers + ends faster than - ends
tread milling is powered by correct answers ATP hydrolysis
profilin correct answers enhances the exchange of ADP for ATP on G actin
cofillin correct answers enhances the rate of loss of ADP actin from the - end
thymosin B4 correct answers provides a reservoir of actin
capping proteins correct answers bind to filament ends blocking assembly and disassembly
rate limiting step in actin filament assembly correct answers is the formation of short actin oligomer that can elongate into filaments
_______ assemble unbranched filaments correct answers formins
FH2 domain correct answers protect + end from being capped and rock back and forth for additional interstion of subunits
FH1 domain correct answers binds profilin comlexed with ATP G actin so fed into the + end on the FH2 domain
________ nucleates the assembly of branched filaments correct answers ARP2/3
ARP2/3 activated by correct answers NPF
NPF activated by correct answers PIP2 and Cdc42
ActA correct answers mimics NPF and activates Arp2/3
fimbrin located correct answers microvilli, filopedia, and focal adheasion
a-actin located in correct answers stress fibers, filopedia, and muscle Z line
spectrin located in correct answers cell cortex

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