HLTH 4340 Substance Abuse & Addiction Comprehensive OA Final Review Q & A 2024 1. Multiple Choice: Which neurotransmitter is most commonly associated with the reward pathway and substance addiction? a) Serotonin b) Dopamine c) GABA d) Acetylcholine Correct Answer: b) Dopamine Rationale: Dopamine is the neurotransmitter most commonly linked to the pleasure and reward pathways in the brain, which are significa ntly affected during substance abuse and addiction. 2. True/False: Physical dependence on a substance is characterized by the presence of withdrawal symptoms when the substance is not taken. Answer: True Rationale: Physical dependence is indicated b y withdrawal symptoms that occur when the substance use is reduced or stopped, reflecting the body's adaptation to the substance. 3. Fill -in-the-Blank: The term "_________" refers to the compulsive seeking and taking of a substance despite adverse consequ ences. Correct Answer: Addiction Rationale: Addiction is defined by compulsive drug -seeking behavior and use, even when faced with negative health and social consequences. 4. Multiple Choice: Which of the following is a criterion for substance use d isorder in the DSM -5? a) Persistent desire or unsuccessful attempts to cut down or control substance use b) Increased tolerance to the substance c) Development of withdrawal symptoms
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