A patient shows the presence of antibodies against diphtheria toxin. Which of the following
statements is FALSE?
A) The patient may have the disease.
B) The patient may have had the disease and has recovered.
C) The patient may have been vaccinated.
D) A recent transfusion may have passively introduced the antibodies.
E) The patient was near someone who had the disease - ANSthe patient was near someone
who had the disease
In an agglutination test, eight serial dilutions to determine antibody titer were set up. Tube #1
contained a 1:2 dilution; tube #2, a 1:4, etc. If tube #6 is the last tube showing agglutination,
what is the antibody titer?
A) 6
B) 1:6
C) 64
D) 1:32
E) 32 - ANS64
An ELISA for Hepatitis C has 95 percent sensitivity and 90 percent specificity. This means that
the test
A) detects 95 percent of the true positive samples and has 10 percent false positive results.
B) detects 5 percent of the true positive samples and has 90 percent false positive results.
C) detects 90 percent of the true positive samples and has 5 percent false positive results.
D) detects 95 percent of the true positive samples and has 90 percent false positive results.
E) detects 5 percent of the true positive samples and has 10 percent false positive results -
ANSdetects 95 percent of the true positive samples and has 10 percent false positive results
Which of the following are sources of antibodies for serological testing?
A) vaccinated animals
B) cells producing monoclonal antibodies
C) viral cultures
D) vaccinated animals and cells producing monoclonal antibodies
E) vaccinated animals, cells producing monoclonal antibodies, and viral culture -
ANSvaccinated animals and cells producing monoclonal antibodies
A reaction between an antibody and soluble antigen-forming lattices is called a(n)
A) agglutination reaction.
B) complement fixation.
A reaction between antibody and particulate antigen is called a(n)
A) agglutination reaction.
B) complement fixation.
C) immunofluorescence.
D) neutralization reaction.
E) precipitation reaction - ANSagglutination reaction
A reaction that uses the absence of hemolysis of red blood cells to indicate an
antigen—antibody reaction is called a(n)
A) agglutination reaction.
B) complement fixation.
C) immunofluorescence.
D) neutralization reaction.
E) precipitation reaction - ANScomplement fixation
A DNA plasmid encoding a protein antigen from West Nile virus is injected into muscle cells of a
horse. This is an example of a(n)
A) subunit vaccine.
B) conjugated vaccine.
C) nucleic acid vaccine.
D) attenuated whole-agent vaccine.
E) live whole-agent vaccine. - ANSnucleic acid vaccine
Toxoid vaccines, such as the vaccines against diphtheria and tetanus, elicit a(n)
A) TC cell response.
B) immune complex.
C) dendritic cell proliferation.
D) antibody response against these bacterial toxins.
E) antibody response against gram-positive bacteria - ANSantibody response against these
bacterial toxins
The clumping of test red blood cells indicates a negative test result (no antibodies against the
virus in the patient's serum) in the
A) direct agglutination test.
B) indirect agglutination test.
C) complement-fixation test.
D) precipitation test.
E) viral hemagglutination inhibition test - ANSviral hemagglutination inhibition test
What type of vaccine involves host synthesis of viral antigens?
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