Exam 2: NSG 124/ NSG 124 (NEW 2024/ 2025 Update) Pharmacology | Review with Questions and Verified Answers| 100% Correct| Graded A - Herzing QUESTION Vancomycin Answer: - inhibits cell wall synthesis - treats MRSA, C. difficile - monitor renal function with creatinine levels - obtain trough level (30 minutes prior to next dose) - infuse slowly, at least over 60 minutes QUESTION Vancomycin adverse effects Answer: - nephrotoxicity - red man syndrome (rash, hives, flushing, itching) - do not stop infusion, just slow it down - thrombophlebitis (inflammation of the vein wall) - switch IV sites QUESTION tetracycline - therapeutic use Answer: - severe acne - Lyme disease - peptic ulcers - periodontal disease - not used often due to bacterial resistance QUESTION macrolides - mechanism of action Answer: - inhibits protein synthesis - broad spectrum antibiotics QUESTION macrolides - medications Answer: - erythromycin - azithromycin - clarithromycin QUESTION macrolides - therapeutic use Answer: - pertussis/whooping cough - diphtheria - chlamydia - pneumonia QUESTION Aminoglycosides Answer: - given IV only due to poor GI absorption - treats gram -negative aerobic bacilli - DO NOT use with IV penicillin - causes nephrotoxicity, ototoxicity - obtain trough level (30 minutes prior to next dose) Ex: gentamicin, tobramycin, amikacin QUESTION sulfonamides Answer: - treatment for UTIs - stop medication if adverse effects occur Ex: trimethoprim/sulfamethoxazole (Bactrim) QUESTION sulfonamides patient education Answer: - take with full glass of water - take on an empty stomach to increase absorption - stop medication if adverse effects occur QUESTION sulfonamides adverse effects Answer: - Stevens -Johnson syndrome - hematologic effects - kernicterus (bilirubin induced brain damage) - renal damage - hyperkalemia (increased potassium) QUESTION Stevens -Johnson Syndrome Answer: A severe reaction (possibly to medication) starts with flu -like symptoms followed by a painful rash that spreads and blisters. QUESTION Tuberculosis caused by Answer: Mycobacterium tuberculosis QUESTION Tuberculosis is a ________________ infection. Answer: primary QUESTION tests for tuberculosis Answer: - TB skin test - chest x -ray - sputum culture QUESTION Isoniazid (INH) Answer: primary drug for treatment of TB QUESTION Isoniazid (INH) adverse effects
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