Test Bank for Molecular Cell Biology 8th Edition by Harvey Lodish, Arnold Berk, Chris A. Kaiser, Monty Krieger, Anthony Bretscher, Hidde Ploegh, Angelika Amon, Kelsey C. Martin
Test Bank for Molecular Cell Biology 8th Edition by Harvey Lodish, Arnold Berk, Chris A. Kaiser, Monty Krieger, Anthony Bretscher, Hidde Ploegh, Angelika Amon, Kelsey C. Martin
Molecular cell biology: Mind maps and important figures
All for this textbook (6)
Written for
University of Southampton (UOS)
Biochemistry
Molecular Recognition
All documents for this subject (3)
Seller
Follow
jadebelboda
Content preview
Ivo Tews Lectures
Molecular Recogniton
Signalling Cascades & Long-Term Responses
Two examples will be discussed in this lecture
Signal coming in and received by the cell and to receive a signal is by a receptor
signal going from outside into the cell.
Signal pipeline into the nucleus
Transcripton in nucleus
So, sequence can be changed
More amplified the signal can be controlled at a
checkpoint
Cytokines- blood cells and immune system
>50 cytokines known
small proteins 5-20 kDa like 150 amino acids in length
released by cells can even stmulate itself
affect other cells
especially important for cells of the immune system
Four distnct structural families: All follow the same principles
•TNF
•IFN
•chemokines
•EPO hematopoeitin
1 EPO molecule and two receptors it is a beta sheet structure for receptor and alpha helix
for protein binding.
can take the receptor and see what’s different in EP types
cytokines share a common structure also among the receptors but the interface between
the receptors is different. Eeptde interacton different.
The cells mature and would change so do this by looking at the cells receptors
Important if you have the right receptor and ligand
Also, dependent on development and cell type
Cells respond differently under development
- Chromatn structure-
- constellaton of the transcripton factors when one set is actve another cell may
have TFs actve as well.
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller jadebelboda. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $6.48. You're not tied to anything after your purchase.