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UNE BIOCHEMISTRY WEEK 7 EVAL QUESTIONS AND ANSWERS
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UNE BIOCHEMISTRY WEEK 7 EVALQUESTIONS AND ANSWERS
Transketolase
Transaldolase is responsible for the transfer of 3 carbon units between sugars in the non-
oxidative portion of the pentose phosphate pathway. Transketolase is responsible for the
transfer of 2 carbon units between sugars in the non-oxidative portion of the pentose
phosphate pathway. - answer In the non-oxidative portion of the pentose phosphate pathway,
2-carbon fragments of keto-sugars can be transferred to other sugars to generate a larger sugar
molecule. This reaction is catalyzed by which of the following enzymes?
Lactate
Glycolysis and the pentose phosphate pathway are the two active pathways for glucose
catabolism in the red blood cells. - answer Red blood cells lack mitochondria; therefore glucose
is primarily oxidized to ribose and which of the following compounds?
Gluconeogenesis and glycogenolysis
Hereditary fructose intolerance can cause bouts of hypoglycemia due to reduced activity of
both gluconeogenesis and glycogenolysis. - answer An 18-month-old is newly diagnosed with
hereditary fructose intolerance (deficiency in Aldolase B). His mother reports he is particularly
upset when he gets up in the morning or if he has not eaten in a while. Laboratory testing
showed low blood glucose levels at the time of presentation. This presentation is likely due to
an accumulation of fructose 1 -phosphate and inhibition of which of the following pathways?
Hypoglycemia
Fructokinase deficiency would largely result in fructose being excreted in the urine. The inability
to phosphorylate fructose would mean fructose could not be trapped in the cell or metabolized
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