Summary of the entire course Preclinical Drug Research (18/20)
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Course
Preclinical Drug Research
Institution
Universiteit Antwerpen (UA)
Summary of the entire course Preclinical Drug Research (18/20): This is a compact summary of the whole course from the subject Preclinical Drug Research (slides, lectures, and all the important information from the insert) & the answers of all the old exam questions from the course Preclinical Drug...
ALLE OUDE EXAMENVRAGEN
PRECLINICAL
EXAMENVRAGEN PRECLINICAL MIJN JAAR 1E ZIT: 09/01/2023
KLEINE VRAGEN (eerste 2 vragen over biopharmaceuticals):
Eerste vraag: Biopharmaceuticals
1) Deelvraag A: Geef definitie van biopharmaceuticals volgens regulatory principle:
2) Deelvraag B: Geef the adventages of biophamaceuticals:
Tweede vraag: Anti-bodies
1) Deelvraag A: Geef 5 different mechanisms of action of Anti-bodies
2) Deelvraag B: Geef 6 different engineering methods of Anti-bodies
Derde vraag: Geef the Weight of Evidence (WoE) factors & leg kort uit en bedenkt een
fictief zelf verzonnen voorbeeld da zeker een Juvenile Animal Studies (JAS) ga moeten doen :
GROTE VRAGEN OVER INSERT (3 deelvragen over Sporanox werkzame stof
Itraconazol):
1. Oral absoprtion: (uitleg geven ik weet nog dat Mw boven 500 was 725
ongeveer) praten over lipinsky rule of 5 enzo!
2. Iets met saturable metabolism en repeated dose: Opzoeken wat saturable
metabolism is Want stond NIET in samenvatting denk.
3. Why do we have to de Carcinogenicity Test & When do we do it (at which
time/which fase?):
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