NUR 2474 Rasmussen Pharmacology Exam 1 dopaminergic agent - ✔✔ levodopa/carbidopa anticholinergic agent - ✔✔ benzotrophine cholinester ase inhibitor - ✔✔ donepezil Immunomodulators - ✔✔ interferon beta traditional anti epileptic drugs - ✔✔ phenytoin, carbamazepine, valproic acid atypical anti epileptic drugs - ✔✔ oxcarbazepine lamotrigdine barbiturates - ✔✔ Phenobarbital muscle spams drugs - ✔✔ baclofen dantrolene 1st generation antipsychotics - ✔✔ low potency: chlorpromazine high potency: haloperidol 2nd generation antipsychotic - ✔✔ clozapine risperdone olanzapine SSRIs - ✔✔ fluoxetine sertraline paroxetine SNRI - ✔✔ venlafaxine duloxetine TCA - ✔✔ amitriptyline MAOI - ✔✔ phenelzine atypical antidepressant - ✔✔ Bupropion, trazodone OTC herbal for depression - ✔✔ ST. Johns Wort mood stabilizer - ✔✔ lithium benzodiazepines - ✔✔ lorazepam, diazepam alprazolam benzodiazepine like drugs - ✔✔ zolpidem insomnia drugs used - ✔✔ trazodone doxepin OTC drug for insomnia - ✔✔ melatonin Atypical Anxiolytic - ✔✔ Buspirone amphetamines - ✔✔ amphetamine, lisdexamfetamine methamphetamine methylxanthines - ✔✔ methylphenidate when should we complete blood testing with use of lithium? - ✔✔ early in therapy - every 2 -3 days, until a therapeutic dose has been established, then long term -every 3 to 6 months therapeutic level of lithium - ✔✔ 0.8-1.4 mEq/L toxic level of lithium - ✔✔ greater than 1.5 mEq/L when can we start to see side effects of lithium? - ✔✔ when the drug is at a therapeutic level. they are expected. what are the side effects of lithium (therapeutic level)? - ✔✔ GI effects, tremors, polyuria, renal toxicity, goiter, hypothyroidism, teratogenesis. what will happen to side effects when one has a toxic level of lithium? - ✔✔ the effects will be much worse and possibly life threatening i.e. tremor that becomes larger with muscle incoordination what medications can we use to treat the cyclic effects of bipolar (mood -depression - psychosis)? - ✔✔ mood stabilizer (lithium)= control mood antidepressant (SSRI,TCA ,MAOI)= control depression antipsychotic (Ist/2nd generation)= control the psychosis how does a benzodiazepine help with ETOH withdrawal? - ✔✔ it will decrease the withdrawal manifestations and intensity, while making one sleepy and having CNS depression. plus, it is easy to give IM and will work quickly.
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