Chapter 09 Alterations in Immunity and Inflammation TEST BANK PATHOPHYSIOLOGY THE BIOLOGIC BASIS FOR DISEASE IN ADULTS AND CHILDREN
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Course
PATHOPHYSIOLOGY
Institution
PATHOPHYSIOLOGY
1. How is hypersensitivity best defined?
a. A disturbance in the immunologic tolerance of self-antigens
b. An immunologic reaction of one person to the tissue of another person
c. An altered immunologic response to an antigen that results in disease
d. An undetectable immune response in the...
Test Bank - Pathophysiology: The Biologic Basis for Disease in Adults and Children (8th Edition)
MULTIPLE CHOICE
, Test Bank - Pathophysiology: The Biologic Basis for Disease in Adults and Children (8th Edition)
1. How is hypersensitivity best defined?
a. A disturbance in the immunologic tolerance of self-antigens
b. An immunologic reaction of one person to the tissue of another person
c. An altered immunologic response to an antigen that results in disease
d. An undetectable immune response in the presence of antigens
ANS: C
Hypersensitivity is an altered immunologic response to an antigen that results in disease or damage to
the host. Autoimmunity is a disturbance in the immunologic tolerance of selfantigens. Alloimmunity
is the immunologic reaction of one person to the tissue of another person. An immune deficiency of
some type would cause undetectable immune response in the presence of antigens.
PTS: 1 DIF: Cognitive Level: Remembering
2. What is a hypersensitivity reaction that produces an allergic response called?
a. Hemolytic shock
b. Anaphylaxis
c. Necrotizing vasculitis
d. Systemic erythematosus
ANS: B
Examples of systemic anaphylaxis are allergic reactions to beestings, peanuts, and fish. Hemolytic
shock would be a state in which erythrocytes are destroyed by complement-mediated lysis to the point
of causing a state of shock. Necrotizing vasculitis is inflammation of blood vessel walls that limits
perfusion. Systemic lupus erythematosus (SLE) is a chronic, multisystem, inflammatory disease and
is one of the most common, complex, and serious of the autoimmune disorders.
PTS: 1 DIF: Cognitive Level: Remembering
3. The common hay fever allergy is expressed through a reaction that is mediated by which class of
immunoglobulins?
a. IgE
b. IgG
c. IgM
d. T cells
ANS: A
Type I reactions are mediated by antigen-specific IgE and the products of tissue mast cells. The most
common allergies (e.g., pollen allergies) are type I reactions. In addition, most type I reactions occur
against environmental antigens and are therefore allergic. Hay fever allergy is not mediated by IgG,
IgM, or T cells.
PTS: 1 DIF: Cognitive Level: Remembering
4. What are blood transfusion reactions an example of?
a. Autoimmunity
b. Alloimmunity
c. Homoimmunity
d. Hypersensitivity
ANS: B
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