NR 566 Week 2 Assignment; HIV National Curriculum - Antiretroviral Therapy
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Course
NR 566
Institution
NR 566
esson 1 Quiz: Antiretroviral Medications and Initial Therapy 1. Question: What result is required for maraviroc to be considered appropriate for use? 2. Question: Which one of the following medications requires phosphorylation to become active as an inhibitor of HIV? 3. Question: According to the A...
1
Maraviroc is being considered as a part of the new antiretroviral regimen and an HIV
tropism coreceptor assay is ordered.
What result is required for maraviroc to be considered appropriate for use?
R5-tropic HIV
Mixed-tropic HIV
X4-tropic HIV
Dual-tropic HIV
2
Which one of the following medications requires phosphorylation to become
active as an inhibitor of HIV?
Etravirine
Lamivudine
Atazanavir
Raltegravir
3
According to the Adult and Adolescent ARV Guidelines, at what CD4 threshold
should antiretroviral therapy by recommended for persons with HIV
infection?
When the CD4 count declines to less than 500 cells/mm3
When the CD4 count declines to less than 200 cells/mm3
When the CD4 count declines to less than 350 cells/mm3
Antiretroviral therapy is recommended for all, regardless of CD4 cell count
4
According to the Adult and Adolescent ARV Guidelines, which one of the
following is classified as a recommended initial regimen for most people with
HIV?
Doravirine-tenofovir DF-emtricitabine
Efavirenz-tenofovir DF-emtricitabine
Dolutegravir plus tenofovir alafenamide-emtricitabine
Darunavir plus ritonavir plus tenofovir alafenamide-emtricitabine
5
What is the mechanism of action of the nucleoside transcriptase inhibitors
(NRTIs)?
Induction of a conformation change in the reverse transcriptase enzyme
Incorporation into the elongating primer strand of HIV DNA with resultant chain termination
Binding to the RNase H region of reverse transcriptase with result separation of the p66 and
p51 subunits
Enzyme inhibition through binding of the polymerase domain binding pocket
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