Gastrointestinal Disease, IBD, and Colorectal Cancer - Summary Notes
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Course
Gastrointestinal (MBCHB)
Institution
The University Of Birmingham (UBir)
A comprehensive, yet concise summary of Gastrointestinal Diseases, IBD, Appendicitis, Colorectal Cancer and more in Medicine/ Surgery, presented in a colourful and digestible format. Includes all relevant information on the topic summarised, collated from multiple resources including lectures, tex...
G1Pathologies
Upper Gl ·
9PIs inhibit
gastric secretions including Intrinsic Factor,
so
they can... cause malabsorption/B12 Deficiency.
Referred for
Foregut Epigastrium 991s be tapered off & notabruptly stopped,
·
is
pain must
·
1
otherwise symptoms return more
severely
·
Gastro-Desophageal Reflux Disease (GORD):due stimulation.
to accumilation of
1. has reduced tone, causing squamous
oesophageal sphincter mucosa
damage from acid reflux.
Squamous epithelium infilrated by Eosinophils/Basophils and
undergoes hyperplasia.
·
and causeoesophagitis and Barret's
metaplasia.
·
can
progress
Barrett's Metaplasia metaplasia from Squamous to Specialised Columnar
-
mild/severe
Treatment:treat differently, escalate if notresponding. Goal is to induce remission.
·
IBDincreases risk Thrombosis in Acute scenario,
of
always give thromboprophylaxis.
so
no steroids
long-term
Aminosalicylates (ASAs): Differentials/Investigations:
e.g. mesalazine.
Acute Therapy: Differentiating IBD and IBS: Faecal Calprotectin and CRP
· ·
-
Oral Prednisalone steroid. are raised during Glinflammation, suggesting IBD over IBS.
Hydrocortisone steroid.
IV
-
-Oral Infliximab antibody. Infections Colitis symptoms of colitis due to
· -
Colon Resection it infection from contaminated food, commonly after travel.
-
responding.
not commonly caused by Shigella, Salmonella, E. Coli.
Do stool culture to rule in/out
infections colitis.
AVOID ANTI-DIARRHOEA DRUGS
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