NYU Pharmacology Exam 2 Questions With Solutions 2023 (Graded A+) NYU pharmacology Exam 2 With Solution Graded A+ 2023/2024 Narrow spectrum penicillin - ANSWER amoxicillin, used for staphylococcus infections Broad spectrum penicillin - ANSWER ampicillin, used for gram + and gram - Extended spectrum penicillin - ANSWER Piperacillin, used for more gram - bone, joint, skin, soft tissue, respiratory tract, urinary tract infections Penicillin MOA - ANSWER interferes with cell wall synthesis, bactericidal Penicillin Adverse reactions - ANSWER GI distress, superinfection, 5%-10% of pts have allergy Penicillin contrainciations - ANSWER hx of allergy/anaphylaxis; renal insufficiency Bactericidal - ANSWER kills bacteria Bacteriostatic - ANSWER inhibits bacterial growth Beta lactamase inhibitor - ANSWER Tazobactam tazobactam use - ANSWER treat bite wound infections, bloodstream infections, DM foot infections, intra-abdominal infections, pneumonia, sepsis Tazobactam Adverse reactions - ANSWER GI distress, superinfection, headache, insomina Cephalosporins MOA - ANSWER inhibit cell wall synthesis; bactericidal Cephalosporins adverse effects - ANSWER GI distress, nephrotoxicity, decresed seizure threshold, 5%-10% allergic 1st generation cephalosporins - ANSWER Cephalexin; only gram + 2nd generation cephalosporins - ANSWER Cefaclor; gram - but not psudomonas 3rd generation cephalosporins - ANSWER ceftrixane; more gram - and crosses the blood brain barrier 4th generation cephalosporins - ANSWER Cefepime; gram - and gram + includes pseudomonas 5th generation cephalosporins - ANSWER Ceftaroline; treatment for MRSA Macrolides - ANSWER Erythromycin Erythromycin MOA - ANSWER inhibits protein synthesis; bacteriostatic and can be bactericidal in large doses
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