NSG 533 Advanced Pharmacology Test 1 Questions With All Correct Answers
Which of the following SSRIs requires up to a 5-week washout period because of the
long half-life of its potent active metabolite?
A. Escitalopram
B. Fluvoxamine
C. Fluoxetine
D. Sertraline - CORRECT ANSWERS ...
NSG 533 Advanced Pharmacology Test 1 Questions With All Correct Answers Which of the following SSRIs requires up to a 5 -week washout period because of the long half -life of its potent active metabolite? A. Escitalopram B. Fluvoxamine C. Fluoxetine D. Sertraline - CORRECT ANSWERS C Which of the following symptoms is most likely to improve within approximately 1 week of starting treatment? A. Depressed mood B. Suicidal thoughts C. Anhedonia D. Sleep - CORRECT ANSWERS D Of the following combinations of medications, which one would you want to avoid? A. Fluoxetine -lithium B. Fluoxetine -phenelzine C. Citalopram -valproic acid D. Citalopram -aripiprazole - CORRECT ANSWERS B A 26-year-old man with a history of depression has been taking sertraline 200 mg/day for 12 weeks with no response. The patient has no other complications. T he physician asks for your recommendation. The most reasonable recommendation would be to: A. Increase sertraline B. Add fluoxetine C. Switch to amitriptyline D. Change to venlafaxine E. Decrease sertraline - CORRECT ANSWERS D Which of the following is a dangerous combination? A. MAOI -lorazepam B. MAOI -acetaminophen C. MAOI -meperidine D. MAOI -ziprasidone - CORRECT ANSWERS C A 23-year-old married white woman comes to the outpatient psychiatric clinic complaining of decreased sleep, decreased appetite, decreased concentration, depressed mood, thoughts of death, and lack of interest in activities for 6 weeks' duration. She has no history of psychiatric illness and takes no medications except for Ortho -Tri Cyclen Lo daily. Based upon the patients symptoms, choose the best medication to treat this patient. NSG 533 Advanced Pharmacology Test 1 Questions With All Correct Answers A. Nefazodone 100 mg po twice daily B. Paroxetine 20 mg po daily C. St. John's wort 300 mg po three times daily D. Amitriptyline 25 mg at bedtime - CORRE CT ANSWERS B A 36-year-old man is admitted to the hospital for a severe methicillin -resistant Staphylococcus aureus diabetic foot infection and is started on linezolid 600 mg IV every 12 hours. His medication profile includes paroxe tine 40 mg every morning, trazodone 100 mg at bedtime as needed for sleep, and metformin 1000 mg po twice daily. After 3 days on these medications, the patient becomes agitated, confused, and diaphoretic and develops myoclonic jerks. Which of the following is the most likely diagnosis? A. Overdose of metformin B. Bacterial meningitis C. Neuroleptic malignant syndrome D. Serotonin syndrome - CORRECT ANSWERS D A 46-year-old woman presents to the psychiatric outpatient clinic for follow -up treatment of major depression. She is currently on paroxetine 10 mg at bedtime, which she started taking 2 months ago when admitted to the psychiatric hospital for suicidal ideation. During the interview, she says that she does not think the medication is working because she is just as depressed as she was before taking the medication and has recently started drinking eight to 10 beers daily to alleviate the depression. Before this episode, she was sober for 4 years. Which of the following treatment str ategies would be the appropriate choice for this patient? A. Stop the paroxetine and start nefazodone 100 mg po twice daily B. Increase the dose of paroxetine to 20 mg po at bedtime C. Stop the paroxetine and start duloxetine 20 mg/day D. Continue the par oxetine at them same dose for a longer period of time to evaluate whether she will respond or not - CORRECT ANSWERS B Which of the following is a flaw in the monoamine hypothesis of depression? A. Concentrations of neurotransmitters are reduced in the synaptic cleft B. A switch to a different class of antidepressants does not improve response C. Antidepressant response is associated with a therapeutic level of the medication D. Antidepressant effects on neurotransmitters do not temporally correspond to response. - CORRECT ANSWERS D
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