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BTEC Assignment Brief
Pearson BTEC Level 3 National Extended Diploma in Applied
Qualification
Science
Unit number and title
Unit 11: Genetics and Genetic engineering
Learning aim(s) (For C: Explore the principles of inheritance and their application in
NQF only) predicting genetic traits
Human inheritance and predicting genetic traits
Assignment title
Assessor
Issue date
Hand in deadline
As a trainee lab technician working for a medical research
company, you must be able to predict patterns of inheritance and
analyse correlations between expected and observed results. Your
company offer work placements for the sixth form students. You
Vocational Scenario or
have been asked to help the sixth form students understand how
Context
an expected ratio of inheritance can be different to an observed
ratio and how statistical tests can determine if this difference is
significant, caused by something or if it is just due to chance.
Task You are required to make valid predictions of patterns of
monohybrid and dihybrid inheritance and then carry out practical
investigations to test your predictions. You must analyse your
data to explain the correlation between the observed patterns of
inheritance and the predictions made.
You must investigate the inheritance of genetic conditions and
apply Mendel’s laws of inheritance to non-affected individuals,
carriers and affected individuals.
In order to do this, you must:
Follow instructions to competently carry out
investigations to collect valid and reliable data for one
monohybrid and one dihybrid phenotypic ratio. You should
demonstrate a very low error rate and gain results close to
the expected.
Produce a write up of your investigations.
Use the data from your investigations, supplemented by
1
BTEC Assignment Brief v1.0
BTEC Internal Assessment QDAM January 2015
, data for peers (if necessary), to effectively apply the chi-
squared test to analyse the correlation between the
observed and expected phenotypic results.
You need to identify if the ratios obtained are statistically
significant or due to chance.
Predict the outcomes of crosses between non-affected,
affected and carriers of genetic disorders. This must
include considering the inheritance of a monohybrid
disorder and a dihybrid disorder but does not have to be
limited to humans.
You must use the data from your investigations and
researched case studies to make these predictions and you
must include an explanation of why the observed ratio for
each example might not be exactly as would be expected.
Analyse data from case studies to explain the genotypic
and phenotypic ratios for crosses involving genetic
conditions in humans or animals.
The case studies must include monohybrid and dihybrid
conditions and must consider the outcomes of crosses
involving unaffected, affected and carrier individuals.
Conditions to consider could include Huntington’s disease,
sickle cell anaemia or cystic fibrosis and linked genes (e.g.
colour blindness or haemophilia).
Use genetic diagrams (e.g. Punnett squares) to represent
the genetic crosses.
Apply Mendel’s laws of independent assortment and
segregation to analyse the results of the genetic crosses.
You should make clear conclusions based on the results.
You must use correct scientific terminology throughout your work
including the following terms:
allele, genotype, phenotype, heterozygous, homozygous,
carrier, affected/sufferer, non-affected/non-sufferer.
Checklist of evidence a write up to include the data from your investigations
required including an accurate prediction and analysis of the outcomes
for both monohybrid and dihybrid inheritance of carrier and
affected individuals and Mendel’s laws
an observation sheet to validate the level of competency when
investigating inheritance
explanation and genetic diagrams of monohybrid genetic
crosses for non-affected, carriers and affected individuals for
both independent and linked genes
Criteria covered by this task:
2
BTEC Assignment Brief v1.0
BTEC Internal Assessment QDAM January 2015
, Unit/Criteria
To achieve the criteria you must show that you are able to:
reference
Make valid predictions on patterns of monohybrid and dihybrid inheritance
C.D3
and variation using principles of inheritance.
Analyse data to explain the correlation between observed pattern of
C.M4
monohybrid and dihybrid inheritance.
C.M5 Apply Mendel’s laws of inheritance to the results of genetic crosses.
Carry out investigations to collect and record data for mono and dihybrid
C.P4
phenotypic ratios.
Explain genetic crosses between non-affected, affected and carriers of
C.P5
genetic conditions.
Sources of information http://www2.le.ac.uk/departments/genetics/vgec/
to support you with schoolscolleges/topics/inheritancepatterns
this Assignment
Above are some examples of websites. Further useful
resources may be found at:
http://qualifications.pearson.com/en/support/published-
resources.html#step1
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