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BIOS242 Final Exam Study GuideThe Final Exam covers chapters 9, 10, 15, 16, 14, 19, 20, 21, 22, 23, and 24.
The exam will be held on Tuesday 18 April 2017 from 1:30 pm – 4:00 pm in
Room
217. I will conduct a review on Monday 17 April 2017 from 10:00 am – 12:00 pm.
The exam consists of 60 MCQ (worth 4 points each) for a total value of 240 points.
TCO 8
• (Ch. 9) Terminology of microbial control
• Sterilization removal/destruction of all microbes
• Aseptic free of microbes and contamination by pathogens
• Antisepsis decrease microbes on living tissue.
• Degerming removal of microbes by scrubbing
• (Ch. 9) Physical methods of microbial control
• Osmotic Pressure hypertonic solutions
• Filtration filter microbes on a porous substance/membrane
• (Ch. 9) Heavy metals
• Arsenic (poison to all)
• Zinc (trace element, sunscreen)
• Mercury (vaccines thimerosal, in excess = toxic)
• Silver (eye drops, aqueous solution)
• Copper (mold resistant)
• Inhibition of bacterial cell walls
• Osmotic Pressure
• Beta-lactams, Vancomycin and Isoniazids
• Actively growing
• (Ch. 10) Inhibition of synthesis of fungal walls
• Composed of various polysaccharides
• Echiocandins inhibit the enzyme that synthesizes glucan; and
without this, fungal cells can’t make cell walls, which leads to
osmotic rupture.
o Polysaccharides, cellulose, ergosterol
• (Ch. 10) Mechanisms of Resistance Gene Acquisition
• Conjugation: donor bacterium, transfers DNA by mating.
• Transduction: DNA introduced into cell by virus
• Transformation: recipient DNA takes up extracellular DNA
• (Ch. 10) Clinical considerations in prescribing antimicrobial drugs
• Readily available, inexpensive, chemically stable, easily administered,
nontoxic/nonallergenic, & selectively toxic against range of
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, BIOS242 Final Exam Study Guide
pathogens.
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