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Class notes

Control of peripheral resistance

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Lecture notes of 5 pages for the course Medicine at QUB (Cardiac Physiology)

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  • March 9, 2022
  • 5
  • 2020/2021
  • Class notes
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PERIPHERALRESISTANCE
The CV system lacks the capacity to perfuse all vascular
beds so we must direct flow where its needed when its
needed
It must reach's
Brain
spmacnic in
Kidneys Mainly flows
to muscle
Liver in
exercise
Muscles




Laminar vs turbulent flow
A Laminar Smooth flow in

layers with quickest at centre of
L lumen
T I n most blood vessels until a

critical velocity
B Turbulent Disordered with extensive mixing
Beyond critical flow past an obstruction
velocity or
clotting more
likely

, Audible bruits murmurs and Korat Koff sounds


Vascular resistance
A In series Different

categories of vessels Arteries
arterioles capillaries venules
veins
More resistance in series the

greater total resistance


B In parallel Within a vascular bed similar categories
of vessels are arranged in parallel
More resistance in parallel LESS TOTAL resistance


Blood flow meast

Doppler flow me try using the doppler shift of Sound
pulses bounced off blood cells to estimate their speed
Fick principle to estimate flow
Venous occlusion piethysmography

Extremity sealed in a watertight
container and its venous drainage
occluded Rate of flow into the

extre ity
is then proportional to the volume

change observed

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