Class notes
Neoplasia and cell growth
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Lecture notes of 14 pages for the course Medicine at QUB (Pathology)
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DISORDERED CELLGROWTHHYPERTROPHY Increase of the SIZE of car
or tin ou e without Ceu division 4 in number
of cars It can occur by itself but often occurs in
combination with hyperplasia
Physiological examples Skeletal muscle
increase with in
that occurs
training
athletes
Myometruirn of uterus
during pregnancy
due to effect of hormones
Pathological examples Cardiac muscle
of left ventricle due to outflow obstruction
E g aortic stones in
narrowing of aortic value
or increased after load
opening hypertension
e.g
degreeofhypertrophy
of High
left ventricle
Heartweight 550g
P T had hypertension
, HYPERPLASIA Increase in the number of cars in
a tissue as a consequence of Calderin noir It can
occur by itself but
usually occurs in combination
with
hypertrophy
Physiological example Adaptive increase in
erythrocyte production leading to increased
individuals
numbers of RBCs in
living at high
altitude the tow pod leads to increased erythropoietin
that stimulates bone marrow erythropoiesis Increase
in RBC number leads to enhanced 02
carriage
Pathological examples PSORIASIS A skin condition
that causes red flaky patches of skin with silver
scales It occurs when the process by which the body
produces skin cars in accelerated S K in corn are
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