A&P 1 MA278/BSC2 Module 4 ase study Human Anatomy & Physiology (Online Lecture)
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A&P 1 MA278/BSC2 Module 4 ase study Human Anatomy & Physiology (Online Lecture) /A&P 1 MA278/BSC2 Module 4 ase study Human Anatomy & Physiology (Online Lecture) /A&P 1 MA278/BSC2 Module 4 ase study Human Anatomy & Physiology (Online Lecture) A&P 1 MA278/BSC2 Module 4 ase study Human Anatomy & P...
aampp 1 ma278bsc2 module 4 ase study human anatomy amp physiology online lecture aampp 1 ma278bsc2 module 4 ase study human anatomy amp physiology online lecture aampp 1 ma278bsc2
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Module 4 Case Study AP1
Question 1
1 out of 1 points
Jordan is now 19-years old. As an infant, Jordan reached many gross motor skill
milestones, such as holding his head up, rolling over, sitting, and standing, at normal
times. However, he was considered a “late walker” because he took his first steps at 17
months. By 2 years old, his parents noticed a hyperlordotic posture while he was
standing. A Gower's sign and Trendelenberg gait were noted by age four. Throughout his
childhood, he suffered progressive muscle weakness, especially in the proximal
musculature of the arms, pelvis, and legs. He required orthotic braces to assist his walking
and was confined to wheelchair ambulation by age 13.
At 16, he was hospitalized with bronchitis requiring antibiotic treatment, but recovered.
Jordan has a history of progressive muscle weakness, but no history of muscle pain or
spasm, chest pain, or irregular heartbeat. The only medications that he normally takes are
calcium and fluoride supplements. Jordan has three siblings. His older and younger sisters
have never had any major medical issues. Jordan’s older brother is also to a wheelchair
with problems similar to Jordan's. No other immediate or distant family members have
musculoskeletal issues.
Jordan’s history aligns most closely with which diagnosis?
Selected Duchenne muscular
Answer:
dystrophy
Question 2
1 out of 1 points
Jordan had a biopsy of the left gastrocnemius muscle when he was 5 years old. Based on
your answer for his diagnosis, describe the microscopic pathological changes that the
pathologist would have noted in her report.
Selected The pathologist would have noted that the small muscle fibers would be
Answer:
rounded, or polygonal, and there would be occasional
hypertrophic fibers. Noted to be groups of small necrotic and regenerating
muscle fibers. The nuclei would occasionally be internal, and the
endomysial connective tissue would be mildly increased. Finally the
perimysium would show early indications of being replaced by fat.
Pestronk, A. (2017, September 1). DMD Pathology. Retrieved April 26,
2018, from https://neuromuscular.wustl.edu/pathol/dmdpath.htm
Respons Great job formatting the reference! You had to track down or go to the
e home page to get the author and many would miss that.
Feedbac
k:
Question 3
1 out of 1 points
This study source was downloaded by 100000824189183 from CourseHero.com on 03-06-2022 13:56:02 GMT -06:00
, Explain, in your own words, why Jordan’s brother appears to have the same
disease and why his sisters are unaffected.
Selected Duchenne muscular dystrophy is an inherited muscle disease that is passed
Answer:
through the x-chromosome to offspring. Women have two x-chromosomes
and primarily only one of them will carry the trait for the disease.
However, boys have only one x-chromosome, so their risk of getting the
disease is much higher. If the father was the carrier of the gene, he would
have the same disease, and regardless Jordan and his brother would have
been affected. Female carriers have a 25% chance of having a daughter
that is a carrier, and 25% chance of having a daughter that is not a carrier.
There is also a 25% chance of having a boy that is affected with this
disease, and 25% chance that she will have an unaffected boy. So, females
having two x-chromosomes helps them in not acquiring this trait with
symptoms or effects of it, since only one chromosome is affected.
Acsadi, G. (2016). Duchenne Muscle Dystrophy. Retrieved April 26, 2018,
from https://rarediseases.org/rare-diseases/duchenne-muscular-dystrophy/
Respons [None Given]
e
Feedbac
k:
Question 4
1 out of 1 points
Jordan’s calves appear enlarged. Which of the following statements explains this
phenomenon?
Selected As his muscles degenerate, the muscle tissue is replaced by collagen and
Answer: adipose tissue.
Question 5
1 out of 1 points
Jordan displayed Gower’s sign at a young age. Which of the following statements
explains why this this true?
Selected The weakness of his proximal leg muscles and erector spinae muscles force
Answer: Jordan to use his arms to push on the floor.
Question 6
0 out of 1 points
Weakness in his erector spinae muscles forces Jordan to assume which
exaggerated position when standing?
Selected Scolios
Answer: is
This study source was downloaded by 100000824189183 from CourseHero.com on 03-06-2022 13:56:02 GMT -06:00
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