Summary
Summary Locomotor Core Conditions
- Course
- Institution
A condensed summary of the locomotor core conditions for the Leeds MBChB year 3 syllabus
[Show more]
Seller
Follow
medicsummaries
Reviews received
Content preview
LOCOMOTOR CORE CONDITIONS SUMMARYCondition Summary Epidemiology Pathophysiology Prognosis Aetiology Risk Factors S/S Investigations DDs Treatment Complications
Deposition of urate Hyperuricaemia
Spontaneous development Pseudo-gout;
crystals within a joint Painful, but Consumption of high- Arthrocentesis with Colchicine (acute);
from hyperuricaemia; urate Rapid-onset severe pain; joint septic arthritis;
(usually the hallux), self-limiting; 90% renal under- purine foods; diuretic use; synovial fluid allopurinol (chronic); Nephrolithiasis; acute
Gout causing attacks of M>F crystals in the joint interact high recurrence excretion and 10% haematological cancer; stiffness/swelling; tophi; analysis; uric acid trauma; RA; corticosteroids; uric acid nephropathy
with phagocytes and trigger erythema; calor reactive arthritis;
acute inflammatory if left untreated renal over-production HTN levels; joint X-ray NSAIDs
acute inflammation psoriatic arthritis
arthritis of urate
PT/OT; simple
Failure in maintenance of Functional decline
Joint pain/stiffness/swelling Bursitis; gout; analgesia; topical
Degenerative balance between cartilage Host of mechanical Obesity; physical/manual and inability to
Incidence increases Chronic, (commonly knees, hips, X-ray (LOSS); CRP;/ pseudo-gout; Diclofenac; NSAID;
Osteoarthritis mechanical and with age/use of joints matrix synthesis and degenerative and biological factors occupation; joint trauma; hands and lower spine); ESR; rheumatoid psoriatic arthritis; gastro-protection; perform ADLs; spinal
(OA) biological deterioration degradation, resulting in that culminate in the high bone mineral density; stenosis (C/L-spine);
M<F disease Heberden’s/Bouchard’s factor; anti-CCP RA; avascular opioids; surgery;
of bony joints reduced bone formation and development of OA low oestrogen status NSAID-related GI
nodes; functional difficulties necrosis intra-articular
increased catabolism bleeding; gout
corticosteroids
Osteoclasts resorb bone and Bone strength Prior fragility fracture;
Complex skeletal Multiple myeloma;
osteoblasts synthesise bone; Fractures determined by bone white; low BMI; alcohol; DEXA scan; X-ray; Bisphosphonates Hip, rib and wrist
disease, characterised White, post- Vertebral fractures (back pain, osteomalacia;
disruption in osteocyte minimised with mineral density, size/ smoking; immobilisation; serum calcium; TFT; (alendronic acid); fractures; jaw
Osteoporosis by low bone density menopausal women function (hormone-controlled) prophylactic shape of bone, bone calcium/vitamin D- kyphosis); pain and swelling creatinine; vitamin D; CKD; PHPT; calcium/vitamin D necrosis associated
and micro-architectural M<F at the fracture site metastatic bone
results in poor bone treatments turnover, micro- deficiency; corticosteroid phosphate; PTH supplementation with bisphosphonates
defects malignancy
remodelling architecture use; hyperthyroidism
Herniation of nucleus Degenerative changes follow Sprain/strain;
pulposus (inner, softer) L-spine most a loss of hydration of the Pain (exacerbated by activity spinal tumour/ Rest (if severe pain);
Prolapsed Degenerative disc
through a weakness in commonly affected, nucleus pulposus and leads Occupation; smoking; and relieved by rest); radicular infection; postural stay active (if non- Surgery-related spinal
Good disease; spinal MRI/CT spine
disc the annulus fibrosus followed by C-spine to a cascade of cellular obesity leg pain; problems bending/ back pain; intra- severe pain); simple cord compression
trauma
(outer, harder) of an M>F events that may result in straightening the back abdominal analgesia; NSAIDs
intervertebral disc prolapse of a disc pathology
Hands (Z-/swan neck/
Inflamed synovium is central Patient education;
Boutonniere deformity, ulnar
to pathogenesis - it shows glucocorticoids;
Rheumatoid Chronic, autoimmune
increased angiogenesis,
Good if patient
Unknown; type II
deviation, Raynaud’s); other
Psoriatic arthritis; DMARDS Work disability; CAD;
type II hypersensitivity Adult on diagnosis is treated Genetic predisposition; (carpal tunnel, rheumatoid ESR/CRP; RF; anti-
arthritis reaction that principally M≤F cellular hyperplasia, and an aggressively hypersensitivity smoking nodules, atherosclerosis, CCP; X-ray infectious arthritis; (methotrexate); increased mortality;
influx of inflammatory cells reaction gout; SLE; OA NSAIDs; joint Carpal tunnel
(RA) affects the joints
and cytokines; high levels of
and early pulmonary fibrosis,
replacement
osteoporosis, morning
metalloproteinases arthroplasty
stiffness, digit subluxation)
Increase incidence in Delayed or OA/RA; gout/
Infection of one or Bacterial virulence factors as Underlying joint disease; Synovial fluid Gram Abx-associated
patients with inadequate Staphylococcus pseudo-gout;
Septic more joint caused by underlying joint well as the immunological treatment can spp.; Streptococcus
joint prosthesis; IVDU; Hot, swollen, tender, stain and culture; haemarthritis; Joint aspiration; allergic reaction;
arthritis haematogenous or host response determines alcohol; DM; previous joint restricted joint with fever blood culture; WCC; IV Abx osteomyelitis; joint
disease/prosthetic lead to joint spp. trauma; bursitis;
direct infection disease development infection; ulceration CRP/ESR destruction
joints destruction cellulitis
www.medicsummaries.com
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller medicsummaries. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $3.90. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
75323 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now