These summaries (in English and provided with many supporting figures from the book) will help you to obtain a great grade for the course 'Genetics' in the first year of Biomedical Sciences at the VU. With learning al my summaries and lecture notes (see my other documents), I finished this course w...
Chapter 6 - genetic linkage and mapping in eukaryotes
March 1, 2021
8
2020/2021
Summary
Subjects
biomedical sciences
genetics
dna
rna
linkage
mapping
eukaryotes
Connected book
Book Title:
Author(s):
Edition:
ISBN:
Edition:
More summaries for
Summary ISE Genetics Analysis and Principles - Genetics Part 2!!
Chapter 1, overview of genetics
Complete Test Bank Genetics Analysis and Principles 7th Edition Brooker Questions & Answers with rationales (Chapter 1-29)
All for this textbook (60)
Written for
Vrije Universiteit Amsterdam (VU)
Bachelor Biomedical Sciences
Genetics
All documents for this subject (37)
1
review
By: daniellevandervoort • 3 year ago
Seller
Follow
simonezweers19
Reviews received
Content preview
Genetics summary – VU BMS 2020/2021
Simone Zweers
Reference: Brooker, Genetics: Analysis and prinicples, 7th edition
Chapter 6: Genetic linkage and mapping in eukaryotes
1
, Genetics summary – VU BMS 2020/2021
Simone Zweers
Reference: Brooker, Genetics: Analysis and prinicples, 7th edition
- Each chromosome carries hundreds – thousands different genes
- Data from genetic crosses are used to construct a genetic map shows the order of
genes along a chromosome
6.1: Overview of linkage
- Synteny = the situation in which two or more genes are located on the same
chromosome
- Genetic linkage = the phenomenon is which genes that are close together on the same
chromosome tend to be transmitted as a unit
- Chromosomes are sometimes called linkage groups group of genes that are linked
together
o Number of linkage groups = number of chromosome types
- Two-factor cross = two different characters in a cross
- Three-factor cross = three different characters in a cross
Bateson and Punnett discovered two genes that did not assort
independently
- Mendel, two-factor cross: 9:3:3:1
- Not this ratio in a cross of sweet peas involving the characters color
and shape
o The F2 generation had a greater proportion of the two
phenotypes found in the P generation they suggested that
the transmission was coupled, the alleles were not assorted
independently
6.2: Relationship between linkage and crossing over
- Crossing over: homologous chromosomes can exchange pieces
with each other the linkage can be altered during meiosis
- the sister chromatids associate with the homologous sister chromatids to form a bivalent
composed of two pairs of sister chromatids in prophase 1 of meiosis 1 crossing
over may occur between sister chromatids of a homologous pair
Crossing over may produce recombinant genotypes
- Figure a: no crossing over occurred
- Figure b: crossing over occurs recombinant cells =
haploid cells after crossing over produce recombinant
offspring
- Nonrecombinant offspring with the same combination of
alleles found in the parental chromosomes
- Genetic recombination when offspring inherit a combination
of two or more alleles or traits that are different from either of
their parents
o Two/more genes are linked, crossing over during
meiosis
o Two/more genes on different chromosomes,
independent assortment
- Recombinant offspring are produced by crossing over
between two homologous chromosomes during meiosis in a
parent, leading to a different combination of alleles along a
chromosome compared to that parent
2
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller simonezweers19. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $3.80. You're not tied to anything after your purchase.
