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CMB2001 Questions and Answer | Latest Update 2024/2025
CMB2001 Questions and Answer | Latest Update 2024/2025
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CMB2001 L01 Questions and Answer | Latest Update 2024/2025
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Consensus sequences are described with IUPAC ambiguous nucleotide codes. W is A or T S is G or C R is G or A Y is T or C What is the span of the core/basal region of the eukaryotic promoter? ~~> -30 to +30nt What elements are in the core region of the eukaryotic promoter? ~~> TATA ...
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Add to cartConsensus sequences are described with IUPAC ambiguous nucleotide codes. W is A or T S is G or C R is G or A Y is T or C What is the span of the core/basal region of the eukaryotic promoter? ~~> -30 to +30nt What elements are in the core region of the eukaryotic promoter? ~~> TATA ...
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CMB2001 Questions and Answer | Latest Update 2024/2025
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Describe how H3Lys9me heterochromatin is formed ~~> H3Lys9me heterochromatin formation: Lys9 deacetylated by HDAC. Suvar39 then methylates lys9. Methylated lys9 is recognised by HP1 and then HP1 binds. HP1 has chromodomain - chromodomains often recognise and bind to methylated lys residue...
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Add to cartDescribe how H3Lys9me heterochromatin is formed ~~> H3Lys9me heterochromatin formation: Lys9 deacetylated by HDAC. Suvar39 then methylates lys9. Methylated lys9 is recognised by HP1 and then HP1 binds. HP1 has chromodomain - chromodomains often recognise and bind to methylated lys residue...
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CMB2001 Questions and Answer | Latest Update 2024/2025
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What is gene expression? ~~> dsDNA is decoded to ssRNA/proteins by an mRNA intermediate using A/U/C/GTPs and RNA polymerase Where is the consensus sequence in prokaryotic promoters? ~~> at -10 and -35 upstream of the the transcription start site What recognises the consensus sequences ...
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Add to cartWhat is gene expression? ~~> dsDNA is decoded to ssRNA/proteins by an mRNA intermediate using A/U/C/GTPs and RNA polymerase Where is the consensus sequence in prokaryotic promoters? ~~> at -10 and -35 upstream of the the transcription start site What recognises the consensus sequences ...
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CMB2001 Questions and Answer | Latest Update 2024/2025
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Core Promoter Elements ~~> TATA box = repetitive sequence of thymine and adenine Initiator (INR) = sequence of pyramidines like thymine and cytosine DPE = downstream promoter elements found along the DNA Common to have >1 promoter but not all of them CpG islands ~~> Sequences high...
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Add to cartCore Promoter Elements ~~> TATA box = repetitive sequence of thymine and adenine Initiator (INR) = sequence of pyramidines like thymine and cytosine DPE = downstream promoter elements found along the DNA Common to have >1 promoter but not all of them CpG islands ~~> Sequences high...
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CMB2001 Questions and Answer | Latest Update 2024/2025
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Why does RNA degradation take place? ~~> Damaged mRNA Incorrectly transcribed/processed mRNA Control gene expression What 2 things control mRNA levels? ~~> Transcription and turnover Why is turnover important? ~~> If mRNA has a ridiculously long half life and doesn't go away,...
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Add to cartWhy does RNA degradation take place? ~~> Damaged mRNA Incorrectly transcribed/processed mRNA Control gene expression What 2 things control mRNA levels? ~~> Transcription and turnover Why is turnover important? ~~> If mRNA has a ridiculously long half life and doesn't go away,...
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CMB2001 Questions and Answer | Latest Update 2024/2025
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Eukaryotic promoters have a basal region which can contain a TATA box, initiator (Lnr), BRE (TFIIV recognition element) and what other element? ~~> Downstream core promoter (DPE) In prokaryotes RNA polymerase requires what co-factor? ~~> 70 sigma factor Forms the holoenzyme The promo...
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Add to cartEukaryotic promoters have a basal region which can contain a TATA box, initiator (Lnr), BRE (TFIIV recognition element) and what other element? ~~> Downstream core promoter (DPE) In prokaryotes RNA polymerase requires what co-factor? ~~> 70 sigma factor Forms the holoenzyme The promo...
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CMB2001 Questions and Answer | Latest Update 2024/2025
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Consensus sequences are described with IUPAC ambiguous nucleotide codes. What is a promoter? ~~> DNA sequence which RNA polymerase can bind to and transcribe the protein Prokaryotic promoters ~~> TATAAT -(10 region) 'Pribnow box' TTGACA - (-35 region) - two consensus sequences P...
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Add to cartConsensus sequences are described with IUPAC ambiguous nucleotide codes. What is a promoter? ~~> DNA sequence which RNA polymerase can bind to and transcribe the protein Prokaryotic promoters ~~> TATAAT -(10 region) 'Pribnow box' TTGACA - (-35 region) - two consensus sequences P...
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CMB2001 – 9 Questions and Answer | Latest Update 2024/2025
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how many proteins are in small subunit of the 70S ribosome ~~> 21 how many proteins are in small subunit of the 80S ribosome ~~> 33 how many proteins are in large subunit of the 70S ribosome ~~> 31 how many proteins are in large subunit of the 80S ribosome ~~> 50 23S and 5S r...
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Add to carthow many proteins are in small subunit of the 70S ribosome ~~> 21 how many proteins are in small subunit of the 80S ribosome ~~> 33 how many proteins are in large subunit of the 70S ribosome ~~> 31 how many proteins are in large subunit of the 80S ribosome ~~> 50 23S and 5S r...
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