PMY 302 EXAM PACKAGE DEAL QUESTIONS & ANSWERS RATED A+

principal determinants of BP - arterial pressures (CO X peripheral resistances) and Cardiac outputs (heart rate, myocardial contractility, blood volumes and venous returns) life style modifications available to tx hypertension - weight loss, sodium regulations, DASH diets, alcohol restriction, ae...

Monoamine Oxidase Inhibitors (MAOIs) - Antidepressant Inhibit activity of MAOs to stop them from breaking down 5HT, NE in synapse and stores, irreversible, takes a few weeks to replace Side effects: Bad reaction with tyramine rich foods "wine-cheese interaction" fatal (MAO-A drugs only) Meper...

On Target ADR - Warfarin is an example. This is a blood thinner so you are prone to stroke. It is doing what it's suppose to be doing, but because it thins your blood you are prone to stroke. (Doing what it should do, but too well maybe...adverse event due to therapeutic action of drug) Allergic...

transdermal skin patch - medicine diffuses through rate controlling membrane and absorbed into the skin idiosyncratic response - rapid, unpredictable, not dose related but immune mediated. (Epi-Pen) due to genetic or metabolic abnormality occurs first exposure. Pharmacology - study of properties...

how do agonists binding to receptors alter cellular processes and cha/nge cellular phenotype - alter expression level of protein and the turnover number of the enzyme stereospecificity - most drugs are asymmetric (chiral or optically active); one stereoisomers binds with much greater affinity to ...

Desmopressin MOA - activates V2 receptors in the kidney's collecting ducts, reabsorbing water into plasma and concentrating the urine (prevents water from leaving the body) Octreotide Acetate and Lanreotide Therapeutic effects - suppresses GH hypersecretions, reduces pituitary adenoma overgrowth...