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[Show more]largely the story of chemical neurotransmission - Modern psychopharmacology is 
 
Anatomically, chemically, and electrically - neurotransmission can be described as 
 
Neurons (nerve cells) - Anatomical neurotransmission occurs through 
 
axoaxonic synapse - synapse between axon of one neuron and ax...
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Add to cartlargely the story of chemical neurotransmission - Modern psychopharmacology is 
 
Anatomically, chemically, and electrically - neurotransmission can be described as 
 
Neurons (nerve cells) - Anatomical neurotransmission occurs through 
 
axoaxonic synapse - synapse between axon of one neuron and ax...
which FGAs are low potency and which ones are high potency? - Low potency FGAs: 
- chlorpromazine (thorazine) 
- mesoridazine (serentil); QTc issues so 2nd line 
- thioridazine (mellaril); QTc issues so 2nd line 
 
High potency FGAs: 
- Fluphenazine (prolixin); available as LAI 
- Haloperidol (Haldo...
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Add to cartwhich FGAs are low potency and which ones are high potency? - Low potency FGAs: 
- chlorpromazine (thorazine) 
- mesoridazine (serentil); QTc issues so 2nd line 
- thioridazine (mellaril); QTc issues so 2nd line 
 
High potency FGAs: 
- Fluphenazine (prolixin); available as LAI 
- Haloperidol (Haldo...
Drugs are given with the goal of: - Disease prevention 
Assist with diagnosis 
Treatment of a disease or condition 
 
Undesired effects of a drug can be altered by interaction with: - drugs 
food 
 
Basis of drug effects * Initiated through receptors - special protein molecules 
located on cell memb...
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Add to cartDrugs are given with the goal of: - Disease prevention 
Assist with diagnosis 
Treatment of a disease or condition 
 
Undesired effects of a drug can be altered by interaction with: - drugs 
food 
 
Basis of drug effects * Initiated through receptors - special protein molecules 
located on cell memb...
Which of the following is considered the pleasure center of the brain? 
A. Cortico-striatal-thalamic-cortical loop 
B. Mesolimbic dopamine pathway 
C. Mesocortical dopamine pathway 
D. None of the above - B. Mesolimbic dopamine pathway 
 
The reactive reward system signals the immediate prospect...
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Add to cartWhich of the following is considered the pleasure center of the brain? 
A. Cortico-striatal-thalamic-cortical loop 
B. Mesolimbic dopamine pathway 
C. Mesocortical dopamine pathway 
D. None of the above - B. Mesolimbic dopamine pathway 
 
The reactive reward system signals the immediate prospect...
Targeting these molecular sites - causes alterations in synaptic transmission that are linked in turn to the therapeutic actions of various psychotropic drugs 
 
Ligand-gated ion channels - same as ionotropic receptors, ion channel linked receptors. all the same receptor/ion-channel complex 
 
ions ...
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Add to cartTargeting these molecular sites - causes alterations in synaptic transmission that are linked in turn to the therapeutic actions of various psychotropic drugs 
 
Ligand-gated ion channels - same as ionotropic receptors, ion channel linked receptors. all the same receptor/ion-channel complex 
 
ions ...
Anatomical Neurotransmission - hard wired synaptic connection carry electrical impulses until synapse where it turns chemical; Communication WITHIN a neuron 
 
Chemical Neurotransmission - Communication BETWEEN neurons; how signals are coded, decoded, transduced and sent along 
 
Synapses are asymme...
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Add to cartAnatomical Neurotransmission - hard wired synaptic connection carry electrical impulses until synapse where it turns chemical; Communication WITHIN a neuron 
 
Chemical Neurotransmission - Communication BETWEEN neurons; how signals are coded, decoded, transduced and sent along 
 
Synapses are asymme...
Psychosis - syndrome, mixture of symptoms that can be associated with different psychotic disorders 
 
Psychosis - defining feature of diagnosis include schizophrenia, substance abuse psychotic disorder, schizophreniform disorder , schizoaffective, delusional disorder, brief psychotic disorder and p...
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Add to cartPsychosis - syndrome, mixture of symptoms that can be associated with different psychotic disorders 
 
Psychosis - defining feature of diagnosis include schizophrenia, substance abuse psychotic disorder, schizophreniform disorder , schizoaffective, delusional disorder, brief psychotic disorder and p...
How psychotropic drugs work - target one of transporters for a neurotransmitter. target receptors coupled to G proteins. target enzymes 
 
Neurotransmitter transport - presynaptic reuptake and vesicular storage. both use a molecular transporter that utilizes a 12 membrane region transporter 
 
SLC 6...
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Add to cartHow psychotropic drugs work - target one of transporters for a neurotransmitter. target receptors coupled to G proteins. target enzymes 
 
Neurotransmitter transport - presynaptic reuptake and vesicular storage. both use a molecular transporter that utilizes a 12 membrane region transporter 
 
SLC 6...
A 12 transmembrane region TRANSPORTER - 30% of psychotropic drugs (wagon) SSRI's 
 
7-transmembrane G-protein linked RECEPTOR - 30% of all psychotropic drugs (receptor with 7 on it) 
antipsychotics, anxiolytics 
 
Enzymes account for ENZYME - 10% of all psychotropic drugs (ghost) 
 
4 transmembrane...
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Add to cartA 12 transmembrane region TRANSPORTER - 30% of psychotropic drugs (wagon) SSRI's 
 
7-transmembrane G-protein linked RECEPTOR - 30% of all psychotropic drugs (receptor with 7 on it) 
antipsychotics, anxiolytics 
 
Enzymes account for ENZYME - 10% of all psychotropic drugs (ghost) 
 
4 transmembrane...
neurons - cells of chemical communication within the brain. have many sizes, shapes 
and lengths that determine function. localization in brain also affects function 
when neurons malfunction - behavioural symptoms occur that may improve or worsen 
with drugs 
general structure of a neuron - dendr...
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Add to cartneurons - cells of chemical communication within the brain. have many sizes, shapes 
and lengths that determine function. localization in brain also affects function 
when neurons malfunction - behavioural symptoms occur that may improve or worsen 
with drugs 
general structure of a neuron - dendr...
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