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INBDE Pharmacology Exam Questions and Answers All Correct

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INBDE Pharmacology Exam Questions and Answers All Correct When is abx premed not required? - Answer- 1. Cardiac pacemaker 2. Rheumatic fever without valvular dysfunction 3. Mitral valve prolapse without valvular regurgitation Penicillins MOA - Answer- Bactericidal: interferes with bacter...

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  • November 21, 2024
  • 13
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers

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INBDE Pharmacology Exam Questions
and Answers All Correct

When is abx premed not required? - Answer- 1. Cardiac pacemaker
2. Rheumatic fever without valvular dysfunction
3. Mitral valve prolapse without valvular regurgitation

Penicillins MOA - Answer- Bactericidal: interferes with bacterial cell wall synthesis
Cell wall synthesis inhibitor = beta-lactam

If a patient is allergic to penicillin, what other class of abx should you avoid? - Answer-
Cephalosporins - chemically related, cross-allergenic

Broadest spectrum penicillin - Answer- ampicillin (gram -)

clavulanic acid in addition to amoxicillin presents with what benefit? - Answer- beta-
lactam resistant

broadest gram negative spectrum of the penicillins? - Answer- ampicillin

Pseudomonas colitis caused by what abx? - Answer- clindamycin

broad spectrum abx are most likely to cause: - Answer- superinfection - can clear out
normal flora

Chloramphenicol is associated with - Answer- aplastic anemia

Tetracycline is associated with _____________ damage. - Answer- liver

Erythromycin is associated with: - Answer- allergic cholestatic hepatitis

Macrolides should be avoided in patients taking: - Answer- digoxin - antiarrhythmic
seldane - antihistamine

Tetracyclines concentrate in _______________________ - Answer- GCF

Clindamycin concentrates in __________________________ - Answer- bone

MOA of Aspirin (ASA) - Answer- COX 1 and 2
irreversible

, messes with GI

MOA of Ibuprofen (Advil, Motrin): - Answer- COX 1 and 2
reversible
messes with kidney

MOA of Naproxen (Aleve) - Answer- COX 1 and 2
reversible

Acetaminophen MOA - Answer- inhibits pain in CNS (not really understood)
messes with liver - avoid with alcohol

Child presents with fever. Want to avoid ____________ because it can cause Reye's
syndrome. - Answer- Aspirin

Feverish child presents. Want to prescribe ____________________ to avoid Reye's
syndrome - Answer- Acetaminophen

Max dose for Ibuprofen - Answer- 3.2 g/day

Max dose for acetaminophen - Answer- 4.0 g/day

Therapeutic effects of aspirin - Answer- 1. Analgesic --inhibit COX 1&2 (PG synthesis)
2. Anti-inflammatory --inhibit COX 1&2 (PG synthesis)
3. Anti-pyretic -- inhibit PG synthesis in tempreature regulation center of
HYPOTHALAMUS
4. Bleeding time -- inhibit TXA2 synthesis --> inhibits plateley aggregation

Toxic effects of aspirin (8) - Answer- 1. occult bleeding for GI
2. tinnitus (ringing of ears)
3. nausea/vomiting
4. metabolic acidosis
5. decreased tubular resorption of uric acid
6. salicylism - toxic condition
7. delirium
8. hyperventilation

Corticosteroids produced in... - Answer- cortex of adrenal gland

Therapeutic effects of steroids - Answer- 1. Analgesic - inhibits phospholipase A2
2. Anti-inflammatory

Steroid side effects (6) - Answer- 1. gastric ulcers
2. immunosuppression
3. acute adrenal insufficiency
4. osteoporosis

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