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APHON CHEMOTHERAPY OVERVIEW EXAM QUESTIONS AND ANSWERS
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APHON CHEMOTHERAPY OVERVIEW EXAMQUESTIONS AND ANSWERS
Preclinical Research The goal of the answer is to provide a safe initial dosage
for people.
Benefits of folic acid for children with lymphoblastic leukaemia
Clinical trials: ANSWER compares two or more treatments in a clinical trial
setting to assess the impact of intervention for a particular condition or disease.
Phase 1 of a clinical trial: ANSWER: How much can you take before losing it?
find the maximum amount of a medicine or drug combination that can be
tolerated.
ID toxicities that restrict dosage: maximum dosage at which less than 33% of
dose-limiting toxicities occur
Phase 1 Clinical Trial Patient: ANSWER with advanced disease, healthy
organs, and resistance to conventional treatments
Phase 2 Clinical Trial: ANSWER validates dose and toxicity data and assesses
the new agent's effectiveness in treating particular cancer types. information
about acute toxicity, medication delivery, and supportive care
Phase 2 Clinical Trial ANSWER patients are often chosen based on their
functional state, detectable tumour size, normal organ function, and realistic life
expectancy. They also typically exhibit minimal to no ANSWER to previous
treatments.
includes patients who have not received treatment with an experimental
medication.
Phase 3 of the clinical trial: ANSWER evaluates the agent's value in relation to
the current treatment. Assess survival, toxicity, responsiveness, and quality of
life.
, Phase 3 clinical trial Patient-ANSWER: Many newly diagnosed patients who
receive treatment and are monitored for a long time
Phase 4 of the Clinical Trial: ANSWER happens following the agent's
availability in the commercial market. attempts to reduce toxicity and adverse
events with a manageable cure rate. emphasises long-term safety more
ANSWER: Institutional Review Board Signing informed permission and
requiring documenting of eligibility, tx, changes, toxicities, and outcome
ensures that human rights and welfare are respected.
Consent that is informed In order to make decisions that align with cultural,
spiritual, and psychosocial values, ANSWER needs sufficient knowledge.
goal, time, and methods, participant rights, potential advantages, likely hazards,
alternative treatments, confidentiality statement, and statement for voluntary
involvement
The function of nursing: ANSWER confirm consent, information given,
instructional materials, lab and radiographic studies finished before treatment,
dosage and timetable, medication prescription, Gather lab samples, record start
and stop times, record patient ANSWERs, and advise family to report
prescriptions.
Pharmacokinetics is the study of how drugs travel through the body, including
absorption, distribution, metabolism, and excretion. Think about how it differs
from dose to dose and from person to person.
broad therapeutic range: the ANSWER dosage needed to elicit AE is higher
than the dosage needed to achieve efficacy in a significant percentage of
patients.
limited therapeutic range—for example, the dosage of anticancer medications
needed to be effective is not significantly lower than the dosage that could cause
fatal toxicities or adverse events.
Children's pharmacokinetic variability in regard to antitumor drugs: ANSWER
age-related variations, changes in the volume of distribution, and clearances in
the liver (doxo, cytox) and kidneys (bleo, mtx)
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