NSG 531 Pharm Exam 1 Questions and Correct Answers the Latest Update
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Course
NSG 531
Institution
NSG 531
what is the site of drug absorption
cell membrane
what is the building block of the cell membrane
phospholipid
phosphate head
in contact with aqueous solution because it is hydrophilic (attracted to water)
fatty acid tails
hydrophobic (repel water)
non-ionized
not charged, always lipi...
✓ concentration of H+ ions; lower pH=higher hydrogen ion concentration
pKa
✓ reflects the acidity of a particular molecule; he lower the pKa the stronger the acid
(& greater ability to donate a proton)
ALAN
✓ if pH<pKa environment is acidic. Acidic environment moves reaction to Left and
Acid is Nonionized
BRAIN
✓ if pH> pKa environment is basic. Basic environment moves reaction to the Right
Acid is Ionized Base Nonionized
Free drug and Albumin
✓ increased total drug concentration is associated with increased free drug in the
plasma and decreased albumin.
What do you need to do if patient is hypoalbuminemic
✓ decrease med dose to prevent drug toxicity (Esp if they have decreased liver and
kidney function)
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