Exam 2 NSG 531 Questions and Correct Answers the Latest Update
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Course
NSG 531
Institution
NSG 531
Ka
volume needed to get 1 mol free drug when 50% of receptors are occupied (high
associated with low free drug & high protein binding)
Kd
amount of drug needed to occupy 50% of receptors (high is associated with high free
drug & low protein binding)
Log dose response curve
X axis is dos...
✓ uses absolute terms (ex. mmHg). steep curve may mean a small change in dosage but
large change in response
quantal responses
✓ y axis is % of responders (% of ppl who respond to therapeutic effect). Ex. seizure
goes away or doesn't
therapeutic index
✓ the ratio between the toxic and therapeutic concentrations of a drug. narrow
therapeutic effect is unsafe (hard to stay out of toxic range)
agonists
✓ activate/stimulate receptor.
full agonist
✓ produces same maximal effect an intrinsic drug
partial agonist
✓ even if all receptors are full, still doesn't reach maximal effect of intrinsic drug
antagonist
✓ blocks or opposes an action
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