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OST 575 Exam Parasites 1&2|Questions with 100% Correct Answers
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OST 575 Exam Parasites 1&2|Questions with 100% Correct Answers
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OST 575 Exam Parasites1&2|Questions with 100% Correct
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How are humans infected by Clonorchiasis (Clonorchis Sinensis, viverrini, velineus)? - ✔ ✔
eating raw, undercooked, pickled or smoked fish
What race is more susceptible to an active liver fluke infection from Clonorchiasis (Clonorchis
Sinensis, viverrini, velineus)? - ✔ ✔ SE asian immigrants
What is the clinical presentation of Clonorchiasis (Clonorchis Sinensis, viverrini, velineus)? -
✔ ✔ Most patients are asymptomatic
--> light infections are <100 flukes
--> eosinophilia is common
Acute symptoms: RUQ pain, indigestion diarrhea, flatulence, fatigue
chronic symptoms: *cholangitis, cholangiocarcinoma*
What are the diagnostic tools for an Clonorchiasis (Clonorchis Sinensis, viverrini,
velineus) infection? - ✔ ✔ Eosinophilia is a CLUE
Egg detection in feces, duodenal aspirates, bile specimens
Serology (not widely available)
*Definitive diagnosis involves identifying adult worms after treatment, at operation, or
at autopsy*
Imaging (US, CT, MRI)
, What is the treatment of Clonorchiasis (Clonorchis Sinensis, viverrini, velineus)?
- ✔ ✔ Praziquantel (higher dose than Schisto)
Albendazole
Mebendazole
What are the different types of helminth parasites? - ✔ ✔ Trichuris
Ascaris
Hookworm
Strongyloides
Why do the heaviest helminth infections occur early in life, followed by a marked decrease
in intensity? - ✔ ✔ *age dépendant changes correlate with Th2 cytokine production*
Th2 response may decrease the intensity of a chronic infection to an anti-inflammatory
environment favorable to both host and parasite survival
Do helminths replicate in the host? - ✔ ✔ NOO (one exception: Strongyloidiasis)
What are common drugs used for helminth infections? - ✔ ✔ Albendazole
Mebendazole
Nitazoxanide
Ivermectin
Praziquantel
Niclosamide
What is the main symptom associated with a hookworm (ancylostoma duodenal, necator
amerianus) infection? - ✔ ✔ Anemia (palm and conjunctiva good to look at to check for anemia)
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