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N115 - Quiz 2 with Correct Answers

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N115 - Quiz 2 with Correct Answers Levodopa - Ans:-dopamine replacement; increase dopamine in brain; used for Parkinson's; AE: N/V, loss of effect, psychosis, postural HTN; -identify high-risk pt -eval therapeutic effects -manage acute loss of effect -minimize adverse effects -minimize adver...

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  • October 23, 2024
  • 17
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • N115
  • N115
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GraceAmelia
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FIRST PUBLISH OCTOBER 2024




N115 - Quiz 2 with Correct Answers


Levodopa - Ans:✔✔-dopamine replacement; increase dopamine in brain; used for Parkinson's; AE: N/V,

loss of effect, psychosis, postural HTN;




-identify high-risk pt


-eval therapeutic effects


-manage acute loss of effect


-minimize adverse effects


-minimize adverse interactions


Carbidopa - Ans:✔✔-dopamine replacement; inhibits peripheral decarboxylase (prevents breakdown of

Levodopa); used for Parkinson's; AE: N/V, loss of effect, psychosis, postural HTN;




-identify high-risk pt


-eval therapeutic effects
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, ©GRACEAMELIA 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED

FIRST PUBLISH OCTOBER 2024




-manage acute loss of effect


-minimize adverse effects


-minimize adverse interactions


Donepezil (Aricept) - Ans:✔✔-acetylcholinesterase inhibitor; increase cholinergic transmission by

reducing ACh metabolism; used for Alzheimer's; AE: N/V, diarrhea, bradycardia, lightheadedness,

insomnia, vivid dreams;




-monitor b/p, HR, HTN


-assess mental status


-assess GI and GU status: urinary frequency incontinence


Memantine (Namenda) - Ans:✔✔-NMDA inhibitor; blocks N-methyl-D-aspartate receptor in ion

channels; used for Alzheimer's; AE: lightheadedness, confusion, headache;




-advise to report SE: restlessness, psychosis, visual hallucinations, stupor


-advise pt to avoid alc, nic




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, ©GRACEAMELIA 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED

FIRST PUBLISH OCTOBER 2024




-teach pt to avoid OTC


Phenytoin (Dilantin) - Ans:✔✔-traditional anti-epileptic; suppresses action potential through inactivation

of sodium channels; used as seizure med;




-cerebellar-vestibular symptoms: nystagmus, ataxia, diplopia, vertigo


-not usually sedating


-cardiac toxicity: Arrhythmias, Hypotension, Gingival hyperplasia, Hirsutism


-Black box warning: SJS (may test for


HLA-B* 1502 if


asian descent)


-Many drug interactions: Induces hepatic microsomal enzymes → can reduce oral contraceptives,

warfarin, glucocorticoids; Phenytoin may be decreased by


diazepam, alcohol, valproic acid, (CYP inhib.; poss breakthrough seizures)


-small increase in dose may cause a large change in blood levels (due to saturation of metabolism and

zero order kinetics): At low blood levels 5-7 days to ready steady state after dosage change; At high

blood levels may take 4-6 weeks before blood levels are stable


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