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Exam (elaborations)

PC 707 Module 1 Questions And Complete Answers

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PC 707 Module 1 Questions And Complete Answers What is the route of medication when taken orally? (1) intestinal tract (2) portal vein (3) liver (4) hepatic artery (5) systemic circulation (6) hepatic vein Where does absorption primarily take place? GI tract and small intestine What is the p...

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  • October 13, 2024
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  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • PC 707
  • PC 707
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PC 707 Module 1 Questions And Complete
Answers

What is the route of medication when taken orally? (1) intestinal tract (2) portal vein (3)

liver (4) hepatic artery (5) systemic circulation (6) hepatic vein




Where does absorption primarily take place? GI tract and small intestine




What is the pharmokinetic process of how much drug ends up in the body? Absorption




Because not all of the administered dosage may be dissolved or absorbed or survive liver

passage, only a fraction of an administered dosage makes it to the bloodstream. This is called

_______. Bioavailability




What is the maximum blood level that is achieved following drug administration? Peak

Blood Level




What is the process of moving drugs throughout the body? Distribution




What protein do most drugs bind to? Albumin

, PC 707 Module 1 Questions And Complete
Answers

If a drug is all bound in protein, is it more or less available? Less available




If a patient has more protein binding, do you need to increase or decrease dosing of the drug?

increase




Drugs that are ________ are not able to activate receptors unless they are free Protein

bound




Stopping or starting a drug that binds to plasma protein changes the free drug levels of other

__________. Protein bound drugs




What is a hypothetical value that reflects the volume in which a drug would need to dissolved to

explain the relationship between dosage and blood levels? Volume distribution




What is a drug that binds to a receptor and activates the receptor to produce a biological

response? Agonist

, PC 707 Module 1 Questions And Complete
Answers
What is a drug that binds to a receptor and does not allow a drug to bind thus making the drug

inactive? Antagonist




Where are most drugs excreted? Kidneys




Where do drugs break down in the body? Liver (via enzymatic processes)




What is the process of changing one chemical into another, and the process either creates or uses

energy? metabolism




Metabolism (Review CYP450 metabolism. Understand the difference between inducers and

inhibitors. What happens if two drugs are taken that use the same pathway?) One may

inhibit and one may enhance the system, it will lead to increases or decreases of different drugs




If enzyme prevent CYP450, what will happen to the drug in the body? Increase in

pharamacologic action of drug

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