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Maryville NURS 611 patho exam 1 Study Guide

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Maryville NURS 611 patho exam 1 Study Guide Apoptosis - Answer-A programmed cell death that is regulated or programmed. Cellular self- destruction for elimination or unwanted cell populations Necrosis - Answer-Rapid loss of the plasma membrane structure, organelle swelling, mitochondria dysfun...

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  • October 6, 2024
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Maryville NURS 611 patho exam 1 Study
Guide

Apoptosis - Answer✔✔-A programmed cell death that is regulated or programmed. Cellular self-

destruction for elimination or unwanted cell populations


Necrosis - Answer✔✔-Rapid loss of the plasma membrane structure, organelle swelling, mitochondria

dysfunction


What is the #1 cause of cellular injury leading to necrosis (especially the kidney and heart) - Answer✔✔-

hypoxia


What is the #1 cause of hypoxia? - Answer✔✔-ischemia


Main component of a cell - Answer✔✔-nucleus


What does the nucleus contain? - Answer✔✔-nucleolus


What is the nucleolus composed of? - Answer✔✔-RNA, most of cellular DNA, DNA binding proteins, and

histones


Why are histone important? - Answer✔✔-histones bind to DNA and fold it into chromosomes

(chromatin) which is essential for cell division


What are ribosomes? - Answer✔✔-RNA-protein complexes (nucleoproteins) that are synthesized in the

nucleolus and secreted into the cytoplasm through pores in the nuclear envelope called nuclear pore

complexes (NPCs)

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Where can ribosomes be found? - Answer✔✔-cytoplasm and rough ER


what are ribosomes chief function? - Answer✔✔-provides sits for cellular protein synthesis


What is the Golgi apparatus (complex)? - Answer✔✔-a network of flatten, smooth membranes and

vesicles frequently located near the nucleus of the cell


What does the Golgi apparatus do? - Answer✔✔-takes proteins from the ER and processes/packages

them into small membrane-bound vesicles called "secretory vesicles, and refines and directs traffic in the

cell


What are lysosomes and what do they do? - Answer✔✔-maintain cellular health by removal of toxic

cellular components, removal of useless organelles, termination of signal transduction, and signals

cellular adaption


How does aging affect lysosomes? - Answer✔✔-leads to progressive loss of lysosomal efficiency which

declines the regenerative capacity of organs and tissue


What functions do lysosomal components integrate? - Answer✔✔-nutrient abundance, energy levels,

and cell stressors and will translate them into instructions that regulate cellular metabolism toward

either proliferation or inactivity


What is mitochondria responsible for? - Answer✔✔-cellular respiration, cellular metabolism , and energy

production


What does the inner membrane of mitochondria contain? - Answer✔✔-enzymes of the respiratory chain

and are essential to the process of oxidative phosphorylation that generates most of the cell's ATP




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The mitochondrial matrix contains what kind of pathways (1), involve what two things (2), and

metabolizes what three things (3)? - Answer✔✔-1- metabolic


2- urea and heme synthesis


3- carbs, proteins, and lipids


What can accumulate intracellularly caused by stresses form metabolic dearangements? - Answer✔✔-

carbs, proteins, and lipids


What is physiologic atrophy? - Answer✔✔-occurs in early development. ex: thymus glad during

childhood


What is pathologic atrophy? - Answer✔✔-occurs as a result of decreases in workload, use, pressure,

blood supply, nutrition, and hormonal stimulation.


Ex: Shrinking of gonads in an adolescent pt in response to decreased hormonal stimulation. and an pt

immobilized in bed for a prolonged time


what is hypertrophy? - Answer✔✔-increase in cell size


Example of beneficial physiologic hypertrophy? - Answer✔✔-hypertrophy of myocardial cells from

endurance training


example of pathologic hypertrophy - Answer✔✔-cardiomegaly in a hypertensive patient


What is hyperplasia? - Answer✔✔-increase in the number of cells


example of compensatory hyperplasia? - Answer✔✔-regeneration of the liver


example of pathological hyperplasia - Answer✔✔-endometrial tissue

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