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COMSAE Cramming Test with Questions and 100% Correct Verified Solutions
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COMSAE Cramming Test withQuestions and 100% Correct Verified
Solutions
Muddy brown pigmented casts in urine, positive urine dipstick for blood but no
RBC under microscope - Answer Rhabdomyolysis
SE of lithium - Answer hypothyroidism and diabetes insipidus,
kidney damage/impairment
If a question asks about a virus related to dead birds... - Answer West Nile, a
flavivirus. No person to person transmission. Diagnosed by ELISA for IgM in serum.
CSF is more specific in acute neurologic disease. Can cause fever, encephalitis, or
meningitis. Transmitted by aedes japonicas mosquito.
Marburg vs Ebola virus - Answer Both are filoviruses with same course, transmitted by
contact with infected bodily fluids. Marburg is less fatal, bleeding is less evere. Ebola
is likely maintained in a reservoir of small animals.
Which enzyme deficiency would INCREASE uracil and orotic acid in blood and urine?
- Answer Ornithine transcarbamoylase
What GLUT transporter is controlled by insulin? - Answer GLUT4, mediates glucose entry
into a cell, found in skeletal/cardiac muscle and fatty tissue. Insulin stimulates glucose
,uptake by bringing GLUT4 to the membrane. No energy needed to move glucose
into cell.
GLUT5 is located in ____ and transports ____ - Answer intestines and sperm; fructose
What is the rate-limiting step of glycolysis? - Answer Phosphofructokinase 1
Mutation of what glycolysis enzyme leads to gestational diabetes? -
Answer Glucokinase, located in liver and beta pancreatic cells
Alcoholic ataxia is related to a deficiency of... - Answer thiamine (B1), which leads
to impaired glucose breakdown of ATP. Give thiamine before dextrose to avoid
precipitation of Wenicke Korsakoff syndrome
Confabulation, personality change, ataxia, memory loss (permanent) in an alcoholic
due to damage to medial dorsal nucleus of thalamus and mammillary bodies - Answer
Wenicke Korsakoff syndrome
Antidote to organophosphate toxicity (ie parathion) - Answer Atropine AND Pralidoxime
PKU (Phenylketonuria) - Autosomal recessive - Answer Deficiency in phenylalanine
hydroxylase, deficiency of tetrahydrobiopterin cofactor (BH4) -- presents with low
pigmentation (blonde hair/blue eyes), microcephaly, mental and growth retardation,
musty body odor, + phenyl ketones in urine, positive Guthrie test (Phe in blood)
Treat with low Phe in diet (no aspartame) and tyrosine becomes essential
MUSTY BODY ODOR = - Answer PKU
, What cardiac defect is most often associated with Turner Syndrome? -
Answer Coarctation of the aorta
Most exotoxins are heat (labile/stabile) - Answer Labile
Most exotoxins are heat (labile/stabile) - Answer Labile
Which exotoxins are heat stabile? - Answer S. aureus and B. cerus (enterotoxin,
food poisoning, no antibiotic treatment)
Neisseria meningitis is a gram ___ _____ - Answer negative diplococci, obligate
intracellular
Bacteroides fragilis is a gram _____ strict ____ and causes _____ - Answer Gram
negative strict anaerobe and causes pelvic or bowl abscess.
Tx: metronidazole or clindamycin + surgical drainage
Culture Media: Gonorrhea - Answer Thayer-Martin (chocolate)
H. influenza - Answer Chocolate
C. diphtheria - Answer Loffler's + Tellurite
Bordetella pertussis - Answer Bordet-Gengou (Potato extract)
M. tuberculosis - Answer Loweenstein-Jensen agat
Legionella - Answer Charcoal yeast extract agar
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