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Exam (elaborations)

MLSP 5511 Exam 1 || very Flawless.

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  • MLSP 5511

Hematopoietic Stem Cell (HSC) correct answers Precursor to ALL blood cells Myeloid Progenitor Cells correct answers -Erythrocytes -Neutrophils -Eosinophils -Basophils -Monocytes -Macrophages Lymphoid Progenitor Cells correct answers -T lymphocytes -B lymphocytes -NK cells How to col...

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  • October 3, 2024
  • 13
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • MLSP 5511
  • MLSP 5511
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MLSP 5511 Exam 1 || very Flawless.
Hematopoietic Stem Cell (HSC) correct answers Precursor to ALL blood cells

Myeloid Progenitor Cells correct answers -Erythrocytes
-Neutrophils
-Eosinophils
-Basophils
-Monocytes
-Macrophages

Lymphoid Progenitor Cells correct answers -T lymphocytes
-B lymphocytes
-NK cells

How to collect HSC's correct answers -Bone marrow aspiration
-Leukopheresis
-Cord blood collection
-Peripheral blood (using G-CSF)

Variolation correct answers Exposing patients to smallpox lesions through the nostrils or under
skin to induce immunity

Cross-Immunity correct answers Jenner took cowpox, infected a child and induced immunity to
smallpox

Miasma Theory correct answers Theory that disease was caused by bad air emanating from
rotting organic material

Herd Immunity correct answers Majority of individuals in a population are vaccinated so that:

-Pathogen reservoir decreases
-Prevents spread of disease to the immunosupressed, elderly, and the young

Inoculation correct answers Introduction of a pathogen into an individual to induce an immune
response

Vaccination correct answers Introduction of a weakened or modified pathogen into an individual
to develop immunity

Innate Immunity correct answers Immunity that is given to humans from birth

4 Types of Innate Immunity correct answers -Anatomic (skin, mucous membranes)
-Physiologic (temp., low pH, chemical mediators)
-Phagocytic
-Inflammatory

, Adaptive Immunity correct answers Immunity to specific foreign microorganisms and molecules

4 Characteristics of Adaptive Immunity correct answers -Antigenic specificity
-Diversity
-Immunologic memory
-Self/non-self recognition

3 Types of Adaptive Immunity correct answers -Active (natural=response to infection ;
artificial=response to vaccination)

-Passive (natural=antibody transfer across placenta ; artificial=antibody injection to help fight
infection

-Adoptive (received from bone marrow transplants)

Immunogen correct answers Substance that induces an immune response (proteins most potent,
followed by polysaccharides)

Antigen correct answers Substance that combines with final products of immune response (think
ANTI-body GEN-erator)

Epitope correct answers Immunologically active region of antigen

Immunogenicity Factors correct answers -Molecule must be recognized as foreign

-Molecular size (most active immunogens have mass > 10,000 daltons)

-Chemical composition and heterogeneity (protein organization contribute to immunogenicity)

-Susceptibility to antigen processing & presentation (large molecules generally more
immunogenic because they're easily phagocytized ; polymers of D-amino acids can't be
processed)

-Immunogen dosage & route of administration (low or high dose can induce tolerance ;
immunogen administered IV goes to spleen, immunogen administered subcutaneously goes to
lymph nodes)

Adjuvant correct answers Substance that is mixed with an antigen to enhance the immune
response

Blood Cell Classification correct answers Based on expression of CD markers on cell surface

T-Helper Cells Express What CD's? correct answers CD4, CD2, CD3, CD5, CD28, CD45

T-Cytotoxic Cells Express What CD's? correct answers CD8, CD2, CD3, CD5, CD28, CD45

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