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Bio Beyond Genetic Replication with Complete Solutions
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Bio Beyond Genetic Replication with Complete Solutions
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Bio Beyond Genetic Replication withComplete Solutions
Data gathered on DNA replication in human cells indicate that the entire process takes
just 8 hours - what is one way this could happen? - ANSWER-There isn't just one
polymerase copying the DNA
DNA Race - ANSWER-C with G, G with C, T with A, A with T
From chromatin, two major processes are needed to prepare for DNA replication. Watch
the video at right - what processes are needed before new DNA can be made? -
ANSWER-DNA has to be uncoiled
Bonds between bases have to be broken
From your exploration of DNA structure and biological macromolecules, what do you
recall is the function of DNA in the cell? - ANSWER-Information storage
How many days is that? - ANSWER-1053.2407407430553
How many hours is that? - ANSWER-25277.77777783333
How many minutes is that? - ANSWER-1516666.66667 Minutes
How many polymerases must be used to reduce the time needed to copy DNA from
about 25,000 hours to 8 hours? - ANSWER-3,125
How many years is that? - ANSWER-3
However, DNA replication presented an interesting problem that wasn't solved until
1966: DNA is opened in one direction and DNA polymerases only work in one direction,
but the two strands of DNA run in opposite directions (they are antiparallel).
Why is this an issue? - ANSWER-One DNA polymerase has to run away from the fork
In prokaryotes, there is typically only one origin of replication with two replication forks -
areas where the DNA is opened up to be copied, like a bubble expanding. In
eukaryotes, there can be many origins, each with two forks. Think back to what you
learned about prokaryotes: why is it possible for prokaryotes to only have one origin? -
ANSWER-They usually have a smaller genome than eukaryotes
In the Replication Race, you learned that DNA Polymerase in humans copies about 33
bases per second. Assuming a total genome size of 3,000,000,000 bases, how many
seconds are needed to copy the human genome once? - ANSWER-91000000
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