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UC NURS 8024 Module 7 Pharm- Questions and Answers
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UC NURS 8024 Module 7 Pharm- Questions and Answers
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UC NURS 8024 Module 7 Pharm- Questions and Answersmonobactams Correct Ans-IV. active against aerobic, gram negative bacteria only. can use
if allergy to PCN. ex: aztreonam
glycopeptides Correct Ans-vancomycin, telavancin, dalbavancin
vancomycin Correct Ans-bactericidal, inhibits cell wall synthesis - kills slower than beta-
lactams. Gram positive only. used for MRSA. oral for C.diff. time dependent killer, more
frequent doses. renally eliminated - need to renal dose
vancomycin ADE Correct Ans-phlebitis, red man syndrome, ototoxicity
aminoglycosides Correct Ans-IV. inhibits protein synthesis-binds to ribosomes, Gram
negatives. bactericidal, ex: gentamicin, tobramycin, amikacin, streptomycin. concentration
dependent killing - want plasma level high. post-antibiotic effects. half life depends on renal
function, if impaired will have longer half life
aminoglycosides ADE Correct Ans-ototoxicity, nephrotoxicity - ATN, neuromuscular
blockade, skin reactions
aminoglycoside indications Correct Ans-aerobic gram negatives.
amikacin - used in MDROs, TB
inhaled tobramycin for P. aeruginosa in CF
, UC NURS 8024 Module 7 Pharm- Questions and Answers
protein synthesis inhibitor agents Correct Ans-tetracyclines, macrolides, clindamycin,
streptogrammins, oxazolidinones, glycylcyclines
tetracyclines Correct Ans-broad spectrum, widespread resistance. bacteriostatic. inhibits
bacterial protein synthesis. ex: doxy, tetra, minocyclines, tigecycline
tetracycline pharmacokinetics Correct Ans-time dependent killing - dosed more often.
absorption impaired by food, dairy products, antacids
beta-lactam antibiotics Correct Ans-inhibit bacterial cell wall synthesis, bactericidal. ex:
penicillins, cephalosporins, cephamycins, carbapenems, monobactams, beta-lactamase
inhibitors
allergic interstitial nephritis Correct Ans-ADE of beta-lactams specifically
1st gen penicillins Correct Ans-narrow spectrum PCN. Ex: PCN VK. effective against Gram
positives
2nd gen penicillins Correct Ans-broader spectrum PCN, effective against Gram positives
and some Gram negatives. ex: amox, amp
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