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NPRO 1100 IBD (Crohn's Disease) Exam Study Guide
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NPRO 1100 IBD (Crohn'sDisease) Exam Study Guide
What is Crohn's disease? - Answer A subacute and chronic inflammation (patchy) of the
GI tract wall that extends through ALL layers. Mouth to anus
Where does Crohn's disease most commonly occur? - Answer In the distal ileum and
ascending colon
What is the pathophysiology of Crohn's Disease? - Answer Inflammation and abscesses
develop into small ulcers that then deepen and are separated creating a cobblestone
appearance.
What happens to the bowel wall and intestinal lumen in Crohn's disease? - Answer The
bowel wall thickens, and the intestinal lumen begins to narrow.
True or false: Crohn's disease involves severe bleeding. - Answer False. Severe
bleeding is usually seen in patients with Ulcerative Colitis. It is not usually common in
Crohn's disease, if it occurs it is mild not severe.
What are signs and symptoms of Crohn's disease? - Answer Diarrhea (5-6 loose stools
per day, RLQ abdominal pain unrelieved by defecation, Abdominal tenderness and
spasm, WT loss and malnutrition, dehydration (due to disrupted absorption), Fever,
Anemia
How is Crohn's disease diagnosed & assessed? - Answer 1. CT scan is indicated to find
bowel wall thickening, edema, obstructions, abscesses and fistulas.
2. A CBC is performed to assess hematocrit and hemoglobin levels (which may be
decreased)
3. WBC (which may be elevated)
4. Colonoscopy
What indicates malnutrition in patients with Crohn's disease? How is it treated? -
Answer Albumin and Protein levels (will be decreased). A liquid diet called enteral
nutrition is provided to give complete nutrition and give the intestines a rest.
What are complications of Crohn's disease? - Answer 1. Intestinal obstruction or
stricture (abnormal narrowing of bodily passage caused by inflammation), fluid and
electrolyte imbalances, perianal disease, malnutrition and malabsorption, fistula and
abscess. COLON CANCER
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