CWS - Etiological Considerations - Part 1(Neuropathy, Diabetes, Venous
insufficiency, Ischemia, Pressure ulcers/injury, Lymphedema, Trauma) Qs & As
What peripheral neuropathy is associated with vitamin B12, thiamine, and folate deficiency?
Correct Ans-alcoholic peripheral neuropathy
- heavy alcohol consumption is a common form of neuropathy
- poor diet and deficiencies in B12, thiamine, and foalte
- may be irreversible
Toxins as a cause of peripheral neuropathy Correct Ans-- any toxic an lead to peripheral
nerve neuropathy
- medications, especially those for cancer, environmental toxins such as lead, mercury,
arsenic, and EtOH
What auto-immune polyneuropathy is frequently preceded by a viral or bacterial infection?
Correct Ans-Guillian-Barre
, CWS - Etiological Considerations - Part 1(Neuropathy, Diabetes, Venous
insufficiency, Ischemia, Pressure ulcers/injury, Lymphedema, Trauma) Qs & As
*cause unknown but often occurs after this
*possible that the virus made the immune system less discriminating of its own cells which
allows some cells to attack the body's own myelin
Sx of Guillian-Barre Correct Ans-varying degrees of weakness and tingling in the legs
symmetrical spread of these sx to the upper extremities and upper body
once clinical manifestations of the disease disappear, the sx usually progress over hours, days,
or weeks
List common causes of autonomic neuropathy Correct Ans-- abnormal protein buildup
- autoimmune disease
- diabetes
- nerve injury
, CWS - Etiological Considerations - Part 1(Neuropathy, Diabetes, Venous
insufficiency, Ischemia, Pressure ulcers/injury, Lymphedema, Trauma) Qs & As
- medications
- chronic illness
- infectious diseases
- inherited disorders
Diabetic neuropathy manifestation Correct Ans-- loss of sweating --> xerosis
- problematic as skin starts to fissure and open (pathway for infection)
- vascular abnormalities of vasodilation can also manifest in conditions such as Charcot
neuropathy
What is the most common form of neuropathy? Correct Ans-peripheral neuropathy
Peripheral neuropathy presentation Correct Ans-- symmetrical
- numbness, paresthesia, pain
- hypersensitive to pain/physical touch (allodynia)
, CWS - Etiological Considerations - Part 1(Neuropathy, Diabetes, Venous
insufficiency, Ischemia, Pressure ulcers/injury, Lymphedema, Trauma) Qs & As
- severe: burning at night, muscle atrophy, paralysis
- loss of deep tendon reflexes as well as vibratory sense
- may affect one single nerve (mononeuropathy) or nerve trunk (mononeuritis multiplex)
Example of mononeuropathy in the LE/UE Correct Ans-peroneal nerve --> foot drop
radial nerve --> wrist drop
Symmetrical progression of peripheral neuropathy from distal to proximal Correct Ans-
stocking-glove distribution
usually start in the longest nerves of the body, so feet and later hands become involved. Sx
then spread up the extremities
