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NURB 3150 GI Drugs Study Set Exam

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NURB 3150 GI Drugs Study Set Exam ...

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  • September 23, 2024
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  • NURB 3150
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NURB 3150 GI Drugs
Study Set Exam
Antacids- action - Answer neutralize gastric acid

Antacids- indications - Answer hyperacidity r/t PUD, gastritis, GERD, heartburn

Antacids- Contraindications - Answer renal failure, electrolyte imbalances, Gi
obstruction

Antacids- Adverse Effects - Answer Aluminum + calcium: constipation

Magnesium: diarrhea

Calcium: kidney stones, rebound hyperacidity

Aluminum + magnesium: fluid retention, hypophosphatemia and Hypermagnesia

Aluminum +phosphate: Hypercalcemia

Long-term use: Metabolic alkalosis (esp sodium bicarbonate)

Antacids reduce Quinolone absorption by ____, so you must admin __ before or after the
dose of abx. - Answer 50%, 2

Give antacids 1 or 2 hours before admin of any other med because they interact with
_____ - Answer absorption

Antacids - Answer Aluminum hydroxide (Amphojel)

Calcium carbonate (Tums)

Magnesium hydroxide (Milk of Magnesia)

Sodium bicarbonate

Aluminum and magnesium hydroxides (Mylanta, Moalox)

H2 receptor Antagonists- action - Answer inhibition of gastric acid secretion

H2- indications - Answer GERD, PUD, erosive esophagitis, stress ulcer prophylaxis,
pathologic gastric hypersecretory conditions, zollinger Ellison syndrome

H2-contraindications - Answer elderly, renal dysfunction, children <12yr

, H2- Adverse effects of Cimetidine - Answer constipation, confusion, dry mouth.

elderly/renal insufficiency- CNS effects , decreased libido, impotence, gynecomastia

H2 - adverse effects of ranitidine and famotidine - Answer thrombocytopenia

Cimetidine interactions - Answer Increases blood concentrations of certain drugs

Smoking ______ the effects of H2 drugs - Answer decreases

You should avoid _______ foods and _______ temperatures when taking H2 drugs -
Answer spicy, extreme

H2 receptor Antagonists - Answer famotidine (Pepcid)

nizatidine (Axid)

ranitidine (Zantac)

cimetidine (Tagamet)

Proton Pump Inhibitors- action - Answer irreversibly blocks gastric acid secretion

PPI- indications - Answer GERD, PUD, Zollinger- Ellison syndrome, NSAID induced
ulcers, stress ulcer prophylaxis.

PPIs are used in combo with antimicrobials to treat _____________ - Answer H. Pylori
infection

H Pylori Prevpac - Answer lansprazole

amoxicillin

clarithromycin

Prevpac dosage - Answer PO BID for 10-14 days

PPI- Adverse Effects - Answer Low incidence: H/A, Diarrhea, N/V, Blood dyscrasias

Long Term use: Inc risk for C.diff, Mg depletion, osteoporosis. Achlorhydia

PPI- interactions - Answer - Inc levels of warfarin, phenytoin, and diazepam

-Dec levels of atazanavir, ketoconazole, ampicillin, iron salts, digoxin

True or false: You should take PPIs with food - Answer False. Take on empty stomach

True or false: You can chew or crush PPIU tablets - Answer False, swallow tablets whole

PPIs - Answer omeprazole (Prilosec)

esomeprazole (Nexium)

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