CMB2001 Questions and Answer | Latest Update 2024/2025
6 views 0 purchase
Course
CMB2001
Institution
CMB2001
Why does RNA degradation take place?
~~> Damaged mRNA
Incorrectly transcribed/processed mRNA
Control gene expression
What 2 things control mRNA levels?
~~> Transcription and turnover
Why is turnover important?
~~> If mRNA has a ridiculously long half life and doesn't go away,...
Helps translation because it helps reinitiation of translation
Stabilises the RNA because most processes that target RNA for degradation
start through either the cap or the poly(A) tail and to get to these you have
to break open the circular structure
Describe Phase 1 of mRNA degradation
✓ ~~> The breakdown of the RNA
Start by either removing the Poly(A) tail and/or the cap to make it accessible
for exonucleases
Decapping enzymes - DCP1, DCP2
Endonucleases - Argonaute, Swt1, Smg6
Deadenylases (remove the poly(A) tail) - Ccr/Not complex
Master01 | September, 2024/2025 | Latest update
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller ExamArsenal. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $12.49. You're not tied to anything after your purchase.
