Exam (elaborations)
Exam (elaborations) NU 643
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ENTAILS QUESTIONS AND ANSWERS
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, classic synaptic neurotransmission - CORRECT ANSWERS-Presynaptic to synaptic topost synaptic
retrograde neurotransmission - CORRECT ANSWERS-Neurotransmitter moves to
opposite direction from post synaptic to presynaptic
Used to limit a response
volume transmission - CORRECT ANSWERS-Neurotransmitter spills over to other
synapses by diffusion
signal transduction cascade - CORRECT ANSWERS-Triggered by chemical
neurotransmitter from presynaptic neuron
-Ligand binds to receptor which is activated to bind to G-protien and series of
messengers
ultimate goal of signal transduction cascade - CORRECT ANSWERS-ultimate goal is to
turn off or on gene (GENE EXPRESSION) and production of phosphoprotien
ultimate targets of signal transmission - CORRECT ANSWERS-to turn on or turn off
genes (Gene Expression) and to produce phosphoprotiens
second messenger - CORRECT ANSWERS-change occurs to bind to G-protien -which
changes to bind to enzyme -which changes and forms second messenger
2nd messenger found? - CORRECT ANSWERS-Intracellular
G-linked protein - CORRECT ANSWERS-Activated by binding to receptor after receptor
has been conformational changed by neurotransmitter.
G-linked protein's role? - CORRECT ANSWERS-Once bound to receptor G-linked
protien changes shape and binds to enzyme which then release second messenger to
next enzyme in signal transduction cascade.
phosphoproteins - CORRECT ANSWERS-Involved in transduction
Phosphoprotiens are target along STC - these change how Neurotransmitter is released
phosphoproteins formed - CORRECT ANSWERS-Helps to send message to gene
One of the end targets along with the gene
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