flow to the site of injury- causes erythema and swelling.
Cytokines Correct-Soluble factors that contribute to the regulation of innate or adaptive
resistance by affecting other neighboring cells. Can be pro-inflammatory or anti-inflammatory.
Can react quickly or be more delayed.
, Exam-NURS 5315 UTA Exam 2 with Complete Solutions
Leukotrines Correct-Released when mast cells degranulate, prolong the inflammatory
process. Cause vasodilation, attract neutrophils, monocytes, and eosinophils.target of
inhibition for singular.
Prostaglandins Correct-Released when mast cells degranulate, are produced by the
arachidonic pathway. Cause vasodilation, platelet aggregation at site of injury, pain, and fever.
Chemotactic factors Correct-Biochemical substance that attracts leukocyte to the site of
inflammation
Neutrophils Correct-Predominant leukocyte at work during the early stages of acute
inflammation
Monocytes Correct-Become macrophages when entering the tissue, responsible for
presenting antigens to the CD4 cell which triggers T-cell immunity and B-cell immunity.
Releases additional cytokines IL1, IL6, TNF.
, Exam-NURS 5315 UTA Exam 2 with Complete Solutions
Cytokine IL1 function Correct-Causes fever, activates phagocytes & lymphocytes and also
increases the release of IL6a
Cytokine IL6 function Correct-Stimulates production of acute phase reactants and
promotes growth and stimulation of RBCs
Cytokine TNF function Correct-Causes fever, increases synthesis of proinflammatory
proteins by liver, causes muscle wasting, induces thrombosis
Cytokine growth factor function Correct-Promotes production and maturation of
neutrophils
Complement Correct-Functions include bacterial lysis, vasodilation and increased vascular
permeability, triggers mast cell degranulation, chemotaxis, and opsonization.
Kinin Correct-Converted to bradykinin which is responsible for pain and chemotaxis, and it
increases vascular permeability and vasodilation.
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